Aggregation-Induced Emission: Recent Advances in Materials and Biomedical Applications.

Angewandte Chemie
Xiaolei Cai, Bin Liu

Abstract

The concept of aggregation-induced emission (AIE) has opened new opportunities in many research fields. Motivated by the unique feature of AIE fluorogens (AIEgens), during the past decade, many AIE molecular probes and AIE nanoparticle (NP) probes have been developed for sensing, imaging and theranostic applications with excellent performance outperforming conventional fluorescent probes. This Review summarizes the latest advancement of AIE molecular probes and AIE NP probes and their emerging biomedical applications. Special focus is to reveal how the AIE probes are evolved with the development of new multifunctional AIEgens, and how new strategies have been developed to overcome the limitations of traditional AIE probes for more translational applications via fluorescence imaging, photoacoustic imaging and image-guided photodynamic/photothermal therapy. The outlook discusses the challenges and future opportunities for AIEgens to advance the biomedical field.

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Citations

Jul 15, 2020·Angewandte Chemie·Frank Würthner
Jul 11, 2020·Angewandte Chemie·Lin LiangWei Wang
Jul 23, 2020·Angewandte Chemie·Minghao ZhangWanxiang Zhao
Sep 10, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Iwona BudziakDaniel M Kamiński
Oct 8, 2020·Topics in Current Chemistry·Juliang YangFan Xia
Nov 20, 2020·Nanoscale Horizons : the Home for Rapid Reports of Exceptional Significance in Nanoscience and Nanotechnolgy·Xiaona ChenHangxiang Wang
Jan 12, 2021·Topics in Current Chemistry·Ting HanBen Zhong Tang
Feb 27, 2021·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Qinghua HuHongqing Wang
Mar 9, 2021·Frontiers in Immunology·Zongwei LiuWeijiang Guan
Mar 17, 2021·Chemistry, an Asian Journal·Tracey LuuYuning Hong
Apr 10, 2021·Topics in Current Chemistry·Harini A Perera, Mingdi Yan
May 5, 2021·Journal of Nanobiotechnology·Wei ZhaoLigong Lu
Jul 10, 2021·ChemistryOpen·Geeta A ZalmiSheshanath V Bhosale
Jul 22, 2021·Chemical Communications : Chem Comm·Guanming LiaoXiaodong Yin
Aug 4, 2021·Advanced Healthcare Materials·Qinggele BorjihanYing-Wei Yang
Jul 29, 2021·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Numan HasanZhiyong Ma
Aug 21, 2021·Advanced Healthcare Materials·Jun DaiShixuan Wang
Aug 22, 2021·Advanced Healthcare Materials·Yuqing WangXing-Jie Liang

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