Aggregation kinetics of the Aβ1-40 peptide monitored by NMR

Chemical Communications : Chem Comm
Giovanni BellomoClaudio Luchinat

Abstract

The aggregation of Aβ1-40 was monitored by solution NMR, which showed a trend complementary to the one observed by ThT-fluorescence. The NMR data support a kinetic model where Aβ1-40 initially aggregates with the reversible formation of oligomeric species, which then irreversibly convert into fibrils.

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Citations

Mar 28, 2019·Chemical Communications : Chem Comm·Jeffrey R BrenderAyyalusamy Ramamoorthy
Nov 2, 2019·Physical Chemistry Chemical Physics : PCCP·Nidhi Katyal, Shashank Deep
Dec 8, 2019·The FEBS Journal·Federica DonnarummaDelia Picone
Apr 18, 2020·Chemical Communications : Chem Comm·Bikash R SahooAyyalusamy Ramamoorthy
Aug 5, 2020·Chemical Communications : Chem Comm·Linda CerofoliniClaudio Luchinat
Sep 22, 2020·Chemical Science·Alexander J DearTuomas P J Knowles
Oct 22, 2020·International Journal of Molecular Sciences·Mona Koder HamidUlf Olsson
Jul 3, 2021·International Journal of Molecular Sciences·Miriam SciaccalugaCinzia Costa
Jun 12, 2019·The Journal of Physical Chemistry Letters·Nasrollah Rezaei-GhalehMarkus Zweckstetter
Dec 5, 2021·The FEBS Journal·Joëlle A J HousmansFrederic Rousseau

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Methods Mentioned

BETA
biopsies
NMR

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