PMID: 6747May 1, 1976

Aggregation of antiacetylcholine drugs in aqueous solution: micellar properties of some diphenylmethane derivatives

The Journal of Pharmacy and Pharmacology
D Attwood

Abstract

Light scattering methods have been used to examine the aggregation in aqueous solution of a series of antiacetylcholine drugs based on the diphenylmethane nucleus. The drugs investigated included adiphenine hydrochloride, piperidolate hydrochloride, benztropine mesylate, orphenadrine hydrochloride, chlorphenoxamine hydrochloride, lachesine hydrochloride, poldine methylsulphate, pipenzolate bromide, clidinium bromide, benzilonium bromide and ambutonium bromide. A micellar pattern of association was established for all compounds and critical micellar concentrations and aggregation numbers have been determined.

References

Nov 1, 1975·The Journal of Pharmacy and Pharmacology·D Attwood, O K Udeala
Oct 1, 1975·The Journal of Pharmacy and Pharmacology·D Attwood, O K Udeala
Nov 1, 1974·The Journal of Pharmacy and Pharmacology·D Attwood, O K Udeala
Feb 1, 1972·Journal of Pharmaceutical Sciences·A Felmeister
Sep 1, 1972·The Journal of Pharmacy and Pharmacology·D Attwood

Citations

May 17, 2005·Colloids and Surfaces. B, Biointerfaces·A N NagappaR C Srivastava
Nov 4, 2011·Journal of the American Chemical Society·Jiadi ZhangPatrick J Walsh
Mar 1, 1978·The Journal of Pharmacy and Pharmacology·D Attwood, J Gibson
Jun 1, 1979·The Journal of Pharmacy and Pharmacology·D Attwood, S P Agarwal
Dec 1, 1985·The Journal of Pharmacy and Pharmacology·A D Atherton, B W Barry

Related Concepts

Acetylcholine Sulfate (1: 1)
Biphenyl Compounds
Drug Formulation Process
Micelles
Scattering, Radiation
Solutions

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