To compare the characteristics and prognosis of cervical cancer in young women (under 30 years) with those of older women (over 30 years). A retrospective study of 2443 patients diagnosed with FIGO stage IA-IIA cervical cancer who underwent surgical procedures between January 1983 and December 2007. Thirty patients (1.2%) were 30 years or younger. The proportion of non-squamous cell carcinoma was higher in patients 30 years or younger compared with in patients over 30 years (14/30, 46.7% vs 10/30, 33.3%; P=0.001). A higher rate of parametrial involvement was found in the younger group of patients compared with those over 30 years (10/30, 33.3% vs 289/2413, 12.0%; P=0.001). Patients under 30 years had a higher rate of distant metastases compared with older patients (60% vs 49.7%; P=0.036). Non-squamous histology, parametrial involvement, a higher rate of distant metastases, and poorer prognosis are more common in women aged 30 or younger with cervical cancer than in older women with the disease.
Declining prevalence of cervicovaginal human papillomavirus infection with age is independent of other risk factors
Immune responses against human papillomavirus (HPV) type 16 virus-like particles in a cohort study of women with cervical intraepithelial neoplasia. I. Differential T-helper and IgG responses in relation to HPV infection and disease outcome
Immune responses against human papillomavirus (HPV) type 16 virus-like particles in a cohort study of women with cervical intraepithelial neoplasia. II. Systemic but not local IgA responses correlate with clearance of HPV-16
Viral load of human papilloma virus 16 as a determinant for development of cervical carcinoma in situ: a nested case-control study
Natural history of cervical human papillomavirus infection in young women: a longitudinal cohort study
Dominant human papillomavirus 16 infection in cervical neoplasia in young Japanese women; study of 881 outpatients
Worldwide human papillomavirus etiology of cervical adenocarcinoma and its cofactors: implications for screening and prevention
Evidence for cervical cancer mortality with screening program in Taiwan, 1981-2010: age-period-cohort model
Comprehensive clinic-pathological characteristics of cervical cancer in southwestern China and the clinical significance of histological type and lymph node metastases in young patients
Young Cervical Cancer Patients May Be More Responsive than Older Patients to Neoadjuvant Chemotherapy Followed by Radical Surgery
Outcomes of patients undergoing radical hysterectomy for cervical cancer of high-risk histological subtypes
Cervical Cancer in Young Women: Do They Have a Worse Prognosis? A Retrospective Cohort Analysis in a Population of Mexico.
Prognostic significance of pretreatment lymphocyte percentage and age at diagnosis in patients with locally advanced cervical cancer treated with definite radiotherapy
Cervical cancer in women under 25 years of age and outside the screening age: Diagnosis profile and long-term outcomes.
Carcinoma, Squamous Cell
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