Aggressive characteristics of cervical cancer in young women in Taiwan

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
Hei-Yu LauKuan-Chong Chao

Abstract

To compare the characteristics and prognosis of cervical cancer in young women (under 30 years) with those of older women (over 30 years). A retrospective study of 2443 patients diagnosed with FIGO stage IA-IIA cervical cancer who underwent surgical procedures between January 1983 and December 2007. Thirty patients (1.2%) were 30 years or younger. The proportion of non-squamous cell carcinoma was higher in patients 30 years or younger compared with in patients over 30 years (14/30, 46.7% vs 10/30, 33.3%; P=0.001). A higher rate of parametrial involvement was found in the younger group of patients compared with those over 30 years (10/30, 33.3% vs 289/2413, 12.0%; P=0.001). Patients under 30 years had a higher rate of distant metastases compared with older patients (60% vs 49.7%; P=0.036). Non-squamous histology, parametrial involvement, a higher rate of distant metastases, and poorer prognosis are more common in women aged 30 or younger with cervical cancer than in older women with the disease.

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Citations

Feb 24, 2016·Clinical Therapeutics·Elizabeth PelkofskiLeigh A Cantrell
Dec 24, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Sonika AgarwalMichael Frumovitz
Sep 7, 2019·Oncotarget·Gennady M ZharinovVladimir N Anisimov
May 11, 2019·Journal of Gynecologic Oncology·Diama Bhadra ValeLuiz Carlos Zeferino
Dec 21, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Julio Cesar TeixeiraLuiz Carlos Zeferinor
May 31, 2021·Journal of Oncology·Emmanuel Kwateng DrokowKai Sun

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