Aggressive multimodality treatment in transitional cell carcinoma of the parafallopian tube: report of 2 cases and review of the literature

Gynecologic Oncology
Fernando Cotait MalufOlavo Feher

Abstract

Primary carcinoma of the fallopian tube is a rare and aggressive cancer. Information regarding its epidemiologic, biologic, and prognostic characteristics is limited; consequently, no standard treatment has been developed. We report the case histories of 2 women with transitional cell carcinoma (TCC) of the parafallopian tube treated with aggressive multimodality therapy, and the literature is reviewed. Two women presented with stage IIB TCC of the parafallopian tube. Both were treated with cytoreductive surgery followed by adjuvant intravenous chemotherapy with cisplatin, gemcitabine, and paclitaxel. Our consolidation treatment consisted of intraperitoneal chemotherapy using the same agents, and 1 patient also received additional hyperthermic chemotherapy with docetaxel. Both patients remain free of disease. In these 2 cases, an aggressive, multimodality regimen proved to be feasible and effective in treating TCC of the parafallopian tube.

References

Mar 6, 1999·The Journal of Obstetrics and Gynaecology Research·S TakeuchiN Toyoda
Jul 21, 2004·Gynecologic Oncology·Séverine CunatPascal Pujol

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Citations

Mar 10, 2017·Applied Immunohistochemistry & Molecular Morphology : AIMM·Catherine ChangPaulette Mhawech-Fauceglia

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