Aggressive natural killer (NK) cell lymphoma: report of a pediatric case and review of the literature

Leukemia & Lymphoma
K OhnumaH Kikuta

Abstract

We report a rare pediatric case of aggressive natural killer (NK) cell lymphoma, characterized by acute onset hepatosplenomegaly and respiratory distress, and infiltration by large granular lymphocytes with the phenotype of CD3-CD16-CD56+. The patient has remained in complete remission after short-pulse intensive chemotherapy, and myeloablative therapy followed by allogeneic bone marrow transplantation. We compare our case with 7 other children with NK cell leukemia reported from other institutions.

References

Dec 1, 1991·American Journal of Hematology·T OkudaS Imashuku
Jul 1, 1989·The Journal of Clinical Investigation·K Kawa-HaK Hirai
Apr 17, 1980·Nature·J E TalmadgeJ R Starkey
Jan 27, 1995·International Journal of Cancer. Journal International Du Cancer·Q TaoG Srivastava
Jan 1, 1996·Leukemia & Lymphoma·A Tefferi

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Citations

Oct 27, 2006·Oral Oncology·Dalal Abdullah Al-HakeemStephen Porter
Jun 27, 1998·Pathology·S DunkleyD Joshua
May 3, 2000·Clinical and Laboratory Haematology·A DekoninckJ L Rummens
Nov 7, 2007·Journal of Pediatric Hematology/oncology·Ann Veronique C EguarasMa Luz U Del Rosario
Apr 6, 2007·The Tohoku Journal of Experimental Medicine·Hisayuki YokoyamaTakeshi Sasaki
Jun 12, 2018·Journal of Pediatric Hematology/oncology·Bo Kyung KimHee Young Shin
May 6, 2009·Journal of Pediatric Hematology/oncology·Isabelle PellierXavier Rialland
Jul 1, 2006·World Journal of Gastroenterology : WJG·Evan S DellonMark W Russo

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