journal cover

Aggressive prostate cancer cell nuclei have reduced stiffness

Biomicrofluidics

Jan 16, 2018

Zeina S KhanFazle Hussain

Abstract

It has been hypothesized that highly metastatic cancer cells have softer nuclei and hence would travel faster through confining environments. Our goal was to prove this untested hypothesis for prostate cells. Our nuclear creep experiments using a microfluidic channel with a narrow const...read more

Mentioned in this Paper

Biological Markers
Environment
Neoplasms
Immortalization
LMNA
Cell Nucleus
Prostate Carcinoma
Primary Malignant Neoplasm
Prostate
Prostate Cancer, Familial
2
29
Paper Details
References
  • References79
  • Citations3
12345...

Aggressive prostate cancer cell nuclei have reduced stiffness

Biomicrofluidics

Jan 16, 2018

Zeina S KhanFazle Hussain

PMID: 29333204

DOI: 10.1063/1.5019728

Abstract

It has been hypothesized that highly metastatic cancer cells have softer nuclei and hence would travel faster through confining environments. Our goal was to prove this untested hypothesis for prostate cells. Our nuclear creep experiments using a microfluidic channel with a narrow const...read more

Mentioned in this Paper

Biological Markers
Environment
Neoplasms
Immortalization
LMNA
Cell Nucleus
Prostate Carcinoma
Primary Malignant Neoplasm
Prostate
Prostate Cancer, Familial
2
29

Related Papers

Paper Details
References
  • References79
  • Citations3
12345...
/papers/aggressive-prostate-cancer-cell-nuclei-have/29333204