Aggressive surgical and chemotherapeutic treatment of advanced pancreatoblastoma associated with tumor thrombus in portal vein

Journal of Pediatric Surgery
Takeo YonekuraAkio Kubota

Abstract

A 3-year-old boy had pancreatoblastoma arising in the pancreatic head and body, with metastasis in the mesenteric lymph nodes, tumor thrombus in the portal vein, and a small metastatic lesion in the left lung. After preoperative chemotherapy, aggressive surgical treatment including resection and reconstruction of the portal and superior mesenteric veins was performed. Postoperative chemotherapy was followed by high-dose chemotherapy and rescue with peripheral blood stem cell transplantation, and he has now been well for 6 years. This is the first surviving pediatric case of advanced pancreatoblastoma treated by aggressive surgical therapy including reconstruction of the portal vein and high-dose chemotherapy followed by peripheral blood stem cell transplantation.

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Citations

Feb 19, 2010·Pediatric Surgery International·Rumi OhataSeiji Kawasaki
Dec 20, 2007·Journal of Pediatric Hematology/oncology·Yong Jik Lee, Jeong Ok Hah
May 2, 2012·Journal of Pediatric Hematology/oncology·Richard D GlickMichael P Laquaglia
May 16, 2012·Journal of Pediatric Hematology/oncology·Chang XuChunyan Wang
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Nov 18, 2020·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Omar ElghawyTamila L Kindwall-Keller
Jun 27, 2021·Pediatric Blood & Cancer·Ewa BienYves Reguerre
Dec 17, 2020·Journal of Pediatric Hematology/oncology·Giulia ReggianiGianni Bisogno

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