Aggressive treatment with noninvasive ventilation for mild acute hypoxemic respiratory failure after cardiovascular surgery: retrospective observational study.

Journal of Cardiothoracic Surgery
Keiko NakazatoAtsuhiro Sakamoto

Abstract

Acute hypoxemic respiratory failure (AHRF) is one of the most serious complications after cardiovascular surgery. It remains unclear whether noninvasive ventilation (NIV) has potential as an effective therapy for AHRF after cardiovascular surgery, although many reports have described the use of NIV for AHRF after extubation. The aim of this study was to investigate the effectiveness of NIV in the early stage of mild AHRF after cardiovascular surgery. We retrospectively analyzed all patients admitted to the intensive care unit after cardiovascular surgery, whose oxygenation transfer (PaO(2)/FIO(2)) deteriorated mildly after extubation, and in whom NIV was initiated. A two-way analysis of variance and the Bonferroni multiple comparisons procedure, the Mann-Whitney test, Fisher's exact test or the χ(2)test was performed. A total of 94 patients with AHRF received NIV, of whom 89 patients (94%) successfully avoided endotracheal intubation (successful group) and five patients required reintubation (reintubation group). All patients, including the reintubated patients, were successfully weaned from mechanical ventilation and discharged from the intensive care unit. In the successful group, PaO(2)/FIO(2) improved and the respiratory ra...Continue Reading

References

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Jan 20, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Manuel García-DelgadoManuel Colmenero

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Citations

Feb 12, 2014·Current Opinion in Anaesthesiology·Manuel García-DelgadoManuel Colmenero
Dec 17, 2014·Current Opinion in Anaesthesiology·Luca CabriniGiovanni Landoni

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

SPSS

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