Aggressiveness, family history of alcoholism, and the heart rate response to alcohol intoxication

Experimental and Clinical Psychopharmacology
Jean-Marc AssaadRichard E Tremblay

Abstract

Some sons of male alcoholics (SOMAs) are characterized by an increased heart rate (HR) response to alcohol intoxication, which is thought to reflect increased sensitivity to alcohol-induced reward. Such a response has also been related to increased physical aggression. However, the confounding effect of aggression in SOMAs may be obscuring the interpretation of these findings. The HR response to alcohol was therefore assessed in 4 groups: high/low aggressive SOMAs and high/low aggressive non-SOMAs. Results indicate that aggressive SOMAs had the highest intoxicated HR response and that they reported the most alcohol consumption. This suggests that in some cases the high comorbidity between alcohol misuse and aggression is related to an increased sensitivity to alcohol-induced reward.

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Citations

Feb 13, 2010·Addiction Biology·John C CrabbeCindy L Ehlers
Aug 9, 2006·Experimental and Clinical Psychopharmacology·Jean-Marc AssaadRichard E Tremblay
Aug 21, 2008·Pharmacology, Biochemistry, and Behavior·Richard L BellJames M Murphy
Apr 16, 2004·Alcoholism, Clinical and Experimental Research·Caroline BrunelleRobert O Pihl
Apr 26, 2006·Alcoholism, Clinical and Experimental Research·Jean-Marc AssaadRichard E Tremblay
Jul 29, 2008·Alcoholism, Clinical and Experimental Research·Robert C Ristuccia, Linda P Spear

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