Aging and biological rhythms in primates

Médecine sciences : M/S
Martine Perret, Fabienne Aujard

Abstract

All living organisms exhibit rhythmic activities in a wide variety of endocrine and behavioural parameters. These biological rhythms are endogenously generated by a circadian clock, and they are entrained by cyclic variations of environmental factors called synchronizers. Aging is associated with changes in amplitude and temporal organization of many daily and seasonal rhythms. In humans, daily rhythms of sleep, thermoregulation and hormonal secretion are severely altered with aging. Except in humans, studies on primates are scarce. However, age-related effects on biological rhythms are relatively consistent among primate species studied to date, including humans. Therefore, non human primates are of valuable use for such investigations. Most studies have been performed on the Rhesus macaque (longevity 35-40 years) and on the gray mouse lemur (longevity 10-12 years). Like in humans, the rest-activity rhythm becomes fragmented in aged primates, and shows an increased activity during the resting period. Aging induces a decrease in amplitude of the body temperature rhythm and an increase in energy consumption. Various hormonal secretions exhibit a decrease with aging, but the rhythmic components of these declines have not always b...Continue Reading

References

Jan 1, 1991·Journal of the American Geriatrics Society·M A Brock
Oct 1, 1994·The Journal of Clinical Endocrinology and Metabolism·A BélangerF Labrie
Oct 1, 1993·The American Journal of Physiology·T A WehrC Bender
Mar 1, 1995·Experimental Gerontology·T H MonkD J Kupfer
Apr 30, 1998·Physiological Reviews·M Florez-Duquet, R B McDonald
Oct 23, 1998·Journal of Biological Rhythms·M W Hurd, M R Ralph
Jun 7, 2000·Chronobiology International·M A Hofman
Jun 10, 2000·Journal of Sleep Research·T H MonkD J Kupfer
Aug 22, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·T D MoscripJ L Weed
Oct 21, 2000·European Journal of Clinical Nutrition·G S RothM A Lane
Jun 19, 2001·Experimental Gerontology·Y Touitou
Jul 10, 2001·The Journal of Clinical Endocrinology and Metabolism·G S RothM A Lane
Nov 14, 2001·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·M Perret, F Aujard
Aug 1, 2002·Proceedings of the National Academy of Sciences of the United States of America·Shin YamazakiGene D Block
Nov 5, 2002·The Journal of Clinical Endocrinology and Metabolism·Michael J WollerEi Terasawa
Apr 16, 2003·Journal of Biological Rhythms·Daniel E KolkerFred W Turek
Jul 13, 2004·Annals of the New York Academy of Sciences·N D Goncharova, B A Lapin
Jul 13, 2004·Annals of the New York Academy of Sciences·H F UrbanskiD K Ingram

❮ Previous
Next ❯

Citations

Aug 29, 2013·Oxidative Medicine and Cellular Longevity·Fabien PifferiFabienne Aujard
Oct 13, 2007·Experimental Gerontology·Fabienne AujardEus J W Van Someren
Apr 1, 2016·Veterinary Ophthalmology·Charline AlleaumeSabine Chahory
Mar 17, 2009·Journal of Affective Disorders·Enrique Gaspar-BarbaAlessandro Serretti
Aug 2, 2011·Ageing Research Reviews·S LanguilleF Aujard
Jun 14, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·J TerrienF Aujard
Apr 7, 2012·Médecine sciences : M/S·Simon GalasGina Devau
Jan 8, 2013·Médecine sciences : M/S·Julia MarchalFabienne Aujard
Jan 1, 2014·Biologie aujourd'hui·Fabien PifferiMartine Perret

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.