Aging does not affect brain patterns of repetition effects associated with perceptual priming of novel objects

Journal of Cognitive Neuroscience
Anja SoldanYaakov Stern


This study examined how aging affects the spatial patterns of repetition effects associated with perceptual priming of unfamiliar visual objects. Healthy young (n = 14) and elderly adults (n = 13) viewed four repetitions of structurally possible and impossible figures while being scanned with blood oxygenation level-dependent functional magnetic resonance imaging. Although explicit recognition memory for the figures was reduced in the elder subjects, repetition priming did not differ across the two age groups. Using multivariate linear modeling, we found that the spatial networks of regions that demonstrated repetition-related increases and decreases in activity were identical in both age groups, although there was a trend for smaller magnitude repetition effects in these networks in the elder adults for objects that had been repeated thrice. Furthermore, repetition-related reductions in activity in the left inferior frontal cortex for possible objects correlated with repetition-related facilitation in reaction time across both young and elder subjects. Repetition-related increases of an initially negative response were observed for both object types in both age groups in parts of the default network, suggesting that less atten...Continue Reading


Oct 31, 2009·Neuropsychology Review·Cindy LustigPatricia A Reuter-Lorenz
Mar 18, 2009·Psychology and Aging·Anja SoldanYaakov Stern
Feb 19, 2009·Memory & Cognition·Anja SoldanYaakov Stern
Feb 1, 2014·Neural Computation·Kirill Makukhin, Scott Bolland
May 1, 2010·Wiley Interdisciplinary Reviews. Cognitive Science·Mara Mather
Feb 15, 2011·Biological Psychiatry·Lisa T EylerDilip V Jeste
Jan 30, 2013·NeuroImage·Nathalie M-P BourquinStephanie Clarke
Feb 22, 2011·Neurobiology of Aging·Patrizia VanniniReisa A Sperling
Jun 26, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jiongjiong YangXiaohong Xu
Jan 30, 2015·Frontiers in Psychology·Soledad Ballesteros, Julia Mayas
Jun 24, 2009·Arquivos de neuro-psiquiatria·Sergio MachadoPedro Ribeiro


Jun 1, 1992·Psychology and Aging·Daniel L SchacterM Valdiserri
Jun 1, 1995·The International Journal of Neuroscience·M Jelicic
Mar 1, 1995·Journal of Experimental Psychology. Learning, Memory, and Cognition·L L LightR Kennison
Apr 9, 1998·Psychology and Aging·D A Fleischman, John D E Gabrieli
Jun 23, 1998·Current Opinion in Neurobiology·C L Wiggs, A Martin
Oct 1, 1998·Neurobiology of Learning and Memory·Daniel L Schacter, Randy L Buckner
Mar 24, 1999·Memory & Cognition·J G Rueckl, S Mathew
Nov 14, 2000·Cerebral Cortex·A D WagnerRandy L Buckner
Feb 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·Marcus E RaichleG L Shulman
Apr 5, 2002·Psychology and Aging·Roberto Cabeza
Aug 30, 2002·Trends in Cognitive Sciences·Patricia A Reuter-Lorenz
Nov 5, 2002·NeuroImage·Roberto CabezaAnthony R McIntosh
May 6, 2003·Journal of Cognitive Neuroscience·Kristen A McKiernanJeffrey R Binder
Aug 21, 2003·Progress in Neurobiology·R N A Henson
Nov 11, 2003·Proceedings of the National Academy of Sciences of the United States of America·Cindy LustigRandy L Buckner
Dec 25, 2003·Psychology and Aging·David B Mitchell, Peter J Bruss
Jan 8, 2004·Journal of Cognitive Neuroscience·Yuhong Jiang, Nancy Kanwisher
Jan 8, 2004·Journal of Cognitive Neuroscience·Eric H SchumacherMark D'Esposito
Jun 9, 2004·Neuron·Cindy Lustig, Randy L Buckner
Dec 17, 2004·Journal of Cognitive Neuroscience·Luigi Maccotta, Randy L Buckner
Mar 8, 2005·Cerebral Cortex·Yaakov SternRonald van Heertum
Apr 1, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Christian J FiebachGernot G Supp
Apr 12, 2005·Neurobiology of Learning and Memory·Sander M DaselaarCees Jonker
Sep 16, 2005·Cerebral Cortex·Jonas PerssonRandy L Buckner
Oct 21, 2005·Journal of Neurophysiology·Rory Sayres, Kalanit Grill-Spector
Nov 5, 2005·NeuroImage·Kristen A McKiernanJeffrey R Binder
Nov 11, 2005·Current Opinion in Neurology·Trey Hedden, John D E Gabrieli
Feb 24, 2006·Journal of Cognitive Neuroscience·Cheryl L GradyGordon Winocur
Mar 4, 2006·Journal of Cognitive Neuroscience·Christine Wu NordahlWilliam J Jagust
Mar 30, 2006·Journal of Experimental Psychology. Learning, Memory, and Cognition·Anja SoldanLynn A Cooper
Apr 1, 2006·Memory·George P StuartNavi Bhagrath
Apr 20, 2006·Neurobiology of Aging·Eric ZarahnYaakov Stern
Jul 25, 2006·Journal of Cognitive Neuroscience·Eleni OrfanidouMatthew H Davis
Nov 14, 2006·Current Opinion in Neurobiology·Lila Davachi
Jan 20, 2007·Science·Malia F MasonC Neil Macrae
Jun 1, 2007·Journal of Cognitive Neuroscience·Jonas PerssonPatricia A Reuter-Lorenz

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