Aging effects on functional auditory and visual processing using fMRI with variable sensory loading.

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Michael CliffSukhwinder S Shergill

Abstract

Traditionally, studies investigating the functional implications of age-related structural brain alterations have focused on higher cognitive processes; by increasing stimulus load, these studies assess behavioral and neurophysiological performance. In order to understand age-related changes in these higher cognitive processes, it is crucial to examine changes in visual and auditory processes that are the gateways to higher cognitive functions. This study provides evidence for age-related functional decline in visual and auditory processing, and regional alterations in functional brain processing, using non-invasive neuroimaging. Using functional magnetic resonance imaging (fMRI), younger (n=11; mean age=31) and older (n=10; mean age=68) adults were imaged while observing flashing checkerboard images (passive visual stimuli) and hearing word lists (passive auditory stimuli) across varying stimuli presentation rates. Younger adults showed greater overall levels of temporal and occipital cortical activation than older adults for both auditory and visual stimuli. The relative change in activity as a function of stimulus presentation rate showed differences between young and older participants. In visual cortex, the older group sho...Continue Reading

References

Sep 1, 1975·Archives of Neurology·V C HachinskiL Symon
Sep 1, 1994·Psychology and Aging·U Lindenberger, P B Baltes
Dec 1, 1993·Vision Research·P D Spear
Aug 22, 1993·The Journal of Comparative Neurology·A Ahmad, P D Spear
Jan 17, 1996·Annals of the New York Academy of Sciences·C L Grady
Nov 1, 1996·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·T A SalthouseD Z Hambrick
Jan 1, 1997·Magnetic Resonance Imaging·M J BrammerS Rabe-Hesketh
May 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·B Rypma, M D'Esposito
Oct 18, 2000·Biological Psychology·C L Grady
Nov 14, 2000·Archives of General Psychiatry·S S ShergillP K McGuire
Aug 17, 2001·Journal of Cognitive Neuroscience·R L BucknerJ C Morris
Nov 2, 2002·Journal of Magnetic Resonance Imaging : JMRI·Edson AmaroPhilip K McGuire
Aug 16, 2003·International Journal of Audiology·Theresa Hnath ChisolmJennifer J Lister
Nov 5, 2003·Nature Reviews. Neuroscience·Mark D'EspositoAdam Gazzaley
Jan 22, 2004·Nature Reviews. Neuroscience·Trey Hedden, John D E Gabrieli
Mar 4, 2005·Journal of the American Geriatrics Society·Susanne A M ValentijnJelle Jolles
Jul 19, 2005·Neurobiology of Aging·M J HerrmannA J Fallgatter
Nov 1, 2005·Brain Research. Cognitive Brain Research·Michael A KisleyHasker P Davis
Feb 24, 2006·Journal of Cognitive Neuroscience·Cheryl L GradyGordon Winocur
Jun 14, 2006·Journal of Cognitive Neuroscience·Michael W L CheeDenise Park
Jan 24, 2007·NeuroImage·Bertrand ThirionJean-Baptiste Poline
Sep 28, 2007·IEEE Transactions on Medical Imaging·Hua Li, Anthony Yezzi
May 21, 2008·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Thomas M DannhauserZuzana Walker
Jan 7, 2009·Neuropsychologia·Patrick C M WongSumitrajit Dhar
Mar 5, 2009·International Journal of Geriatric Psychiatry·Joanne E RoddaZuzana Walker
Nov 19, 2010·Acta Psychiatrica Scandinavica·C SmeeS Shergill
Sep 2, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jonathan E PeelleArthur Wingfield

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Citations

Nov 26, 2014·Neuropsychology Review·Jennifer C TomaszczykRobin E A Green
Dec 3, 2014·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Derek K TracySukhwinder S Shergill
Apr 14, 2015·CNS Neuroscience & Therapeutics·Chun-Chao HuangChing-Po Lin
Jun 1, 2016·Frontiers in Neuroscience·Velia Cardin
Nov 20, 2015·BioMed Research International·Liliana Ramona DemenescuKlaus Mathiak
Oct 25, 2016·NeuroImage·Javier Gonzalez-CastilloPeter A Bandettini
Nov 16, 2014·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Simon J G Lewis, James M Shine
Feb 13, 2015·Journal of Neurophysiology·Gaelle S L CoullonHolly Bridge
May 19, 2018·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Allison M McKendrickBao N Nguyen
Dec 14, 2018·Frontiers in Neuroscience·Jennifer L AgustusJason D Warren
Jun 6, 2018·Frontiers in Human Neuroscience·Cassandra J BrooksAllison M McKendrick
Jun 12, 2021·Psychophysiology·Yuguang ZhaoBart Rypma
Jun 12, 2021·Annals of the New York Academy of Sciences·Zahra JafariMajid H Mohajerani

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