Agitation effects on submerged growth and product formation of Aspergillus niger

Bioprocess and Biosystems Engineering
S KellyD C Hempel

Abstract

Product formation of mycelial organisms, like Aspergillus niger, is intimately connected with their morphology. Pellet morphology is often requested for product formation. Therefore, it is important to reveal the influence of the hydrodynamic conditions on the morphological development. In the present study, pellet morphology and glucoamylase formation were studied under different agitation intensities of A. niger AB1.13. For pellet formation inside the bioreactor, without the use of precultures, it is necessary to work at low energy dissipation rates. Biomass growth and glucoamylase activity were correlated with energy dissipation. Furthermore, product yield was analysed in dependence of pellet size and concentration. The present work shows that simple equations based on Monod-kinetics can describe growth and product formation, in general, also in mycelian organisms. All measured morphological data, like pellet concentration, as well as glucoamylase formation, strongly depend on the hydrodynamic conditions.

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Citations

Dec 1, 2005·Applied Microbiology and Biotechnology·L H GrimmD C Hempel
Feb 22, 2012·Applied Biochemistry and Biotechnology·Marcel Gutiérrez-CorreaGretty K Villena
Aug 28, 2009·Critical Reviews in Biotechnology·Pardeep Kumar, T Satyanarayana
Nov 28, 2012·Trends in Biotechnology·Andreas E PoschOliver Spadiut
Dec 25, 2015·Biotechnology for Biofuels·Meng-Lei XiaHong-Zhang Chen
Oct 13, 2009·New Biotechnology·Adriana Knob, Eleonora Cano Carmona
Jul 3, 2007·Journal of Biotechnology·Marcin Bizukojc, Stanislaw Ledakowicz
May 8, 2009·Biotechnology and Bioengineering·A HilleH Horn
Jan 19, 2012·Biotechnology and Bioengineering·Liang YuShulin Chen
Mar 6, 2012·Biotechnology and Bioengineering·Rachid BannariPierre Proulx
Dec 3, 2009·Biotechnology and Bioengineering·Habib DriouchChristoph Wittmann
Jul 10, 2012·Journal of Biotechnology·Rainer KrullChristoph Wittmann
Jan 2, 2015·Bioprocess and Biosystems Engineering·Hongzhong LuHenk Noorman
Jul 13, 2007·Biotechnology and Bioengineering·P-J LinR Krull
Sep 2, 2005·Biotechnology and Bioengineering·A HilleH Horn
Nov 1, 2017·Journal of Food Science and Technology·Zheng ZhangFengyun Zhao
Aug 29, 2020·Water Science and Technology : a Journal of the International Association on Water Pollution Research·F SpennatiG Munz

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