PMID: 8606618Jan 1, 1996Paper

Agmatine treatment is neuroprotective in rodent brain injury models

Life Sciences
Gad M GiladVarda H Gilad

Abstract

Agmatine is a naturally occurring guanidino compound, found in bacteria and plants, with several proposed nervous system-related functions suggestive of beneficial effects in central nervous system injury. Here evidence is presented that agmatine can exert potent neuroprotection in both in vitro and in vivo rodent models of neurotoxic and ischemic brain injuries. The cumulative evidence lead us to suggest that agmatine, a relatively nontoxic compound, be tried for potential therapeutic use after neurotrauma and in neurodegenerative disorders.

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Citations

Jan 31, 2004·Pharmacology, Biochemistry, and Behavior·Rui-Bin SuJin Li
Jun 7, 2005·Physiology & Behavior·Feyza Aricioglu, Soundar Regunathan
Apr 4, 2003·Behavioural Brain Research·Daniel LavinskyCarlos Alexandre Netto
Mar 29, 2001·Progress in Neurobiology·H Wiesinger
Feb 28, 2002·Free Radical Biology & Medicine·Sang-Hyun ChoiBoe-Gwun Chun
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Sep 14, 2000·Proceedings of the National Academy of Sciences of the United States of America·C A FairbanksG L Wilcox
Feb 15, 2012·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·S HongG J Seong
May 23, 2012·World Journal of Gastroenterology : WJG·Abeer A Al Masri, Eman El Eter
Oct 14, 2005·Journal of the Peripheral Nervous System : JPNS·Leonard BerenholzGad M Gilad
Jan 4, 2012·Pharmacology & Therapeutics·Gerhard J Molderings, Britta Haenisch
Aug 24, 2007·Pharmacology, Biochemistry, and Behavior·B LewisS Barron
Jan 27, 2017·The Journal of Laryngology and Otology·O SurmeliogluS Polat
Jul 21, 1998·Annals of the New York Academy of Sciences·J BusciglioO Toussaint

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