Agminate and plaque-type blue nevus combined with lentigo, associated with follicular cyst and eccrine changes: a variant of speckled lentiginous nevus

Dermatology : International Journal for Clinical and Investigative Dermatology
R BettiC Crosti

Abstract

Agminate and plaque-type blue nevi are rarely described. We report the occurrence of such a type of blue nevus associated with eccrine changes and a follicular cyst all arising on a macular brown background in a 38-year-old man. The patient presented numerous blue papules and a plaque, overlapping a light tan patch present since birth, on his left thigh. In addition, within the plaque, 3 papules, discharging at intervals a serous fluid, were present. Since the lesion hardened and enlarged, it was surgically excised. Histologic findings revealed a lentigo pattern of the epidermis, corresponding to the light tan macular background and a plaque-type blue nevus, and areas of eccrine ductal proliferations with a ruptured follicular cyst. The association of agminate and plaque-type blue nevus, arising on a light brown patch of lentigo, might represent a variant of speckled lentiginous nevus. Eccrine proliferations may be reactive in nature or represent a more complex hamartomatous lesion. The possibility of malignant transformation and the recent enlargement of the lesion caused by the ruptured follicular cyst convinced us to carry out a wide surgical excision.

Citations

Oct 25, 2003·Journal of the American Academy of Dermatology·Caroline BevonaHensin Tsao
Nov 24, 1999·International Journal of Dermatology·Y M ParkB K Cho
Feb 1, 1994·Journal of Cutaneous Pathology·N MisagoH Kohda
Oct 6, 2005·Dermatology : International Journal for Clinical and Investigative Dermatology·Susanna K Fistarol, Peter H Itin
Dec 2, 2005·Dermatology : International Journal for Clinical and Investigative Dermatology·Helena Vidaurri-de la Cruz, Rudolf Happle
Aug 8, 2015·Journal of Cutaneous Pathology·Heather K SchopperKarolyn A Wanat
May 10, 2011·Clinics in Laboratory Medicine·Maya Zayour, Rossitza Lazova
May 10, 2011·Clinics in Laboratory Medicine·Pushkar A Phadke, Artur Zembowicz
Sep 1, 2009·Surgical Pathology Clinics·Maya Zayour, Rossitza Lazova
Sep 1, 2009·Surgical Pathology Clinics·Pushkar A Phadke, Artur Zembowicz
Oct 27, 2004·Histopathology·A Zembowicz, M C Mihm
Jul 27, 2005·The Journal of Dermatology·Kei YoneyamaHiroshi Shinkai
Mar 4, 2011·Archives of Pathology & Laboratory Medicine·Artur Zembowicz, Pushkar A Phadke

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