Agminated Spitz nevi arising on a nevus spilus after chemotherapy

Pediatric Dermatology
Khaled AidaKamoun Mohamed Ridha

Abstract

Agminated Spitz nevus arising on a background of nevus spilus (NS) is a rare condition. We report here a further case in a child that is original because it is induced by chemotherapy. A 3-year-old boy presented 3 months after the onset of a chemotherapy for a vesico-prostatic rhabdomyosarcoma, multiple pigmented papulo-nodules located on the face, neck, chest wall, and the higher back. These lesions have arose on a pre-existent large congenital histologically confirmed nevus spilus extending along the face, neck, the left shoulder and the left chest wall. Histological examination of three excised nodules led to the diagnosis of Spitz nevus. Our patient may have a high risk for melanoma since he has many criteria predisposing to this risk. Some of these criteria are related to NS but we should also take into account the chemotherapy induction and the high number of Spitz nevi.

References

Jan 1, 1994·Dermatology : International Journal for Clinical and Investigative Dermatology·R Hofmann-WellenhofH Kerl
Jan 15, 2005·Journal of the European Academy of Dermatology and Venereology : JEADV·D Calista
May 31, 2006·Annales de dermatologie et de vénéréologie·S AbecassisM-F Avril

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Citations

Jun 21, 2013·Dermatology Practical & Conceptual·Michael Bär
Feb 4, 2012·Journal of the American Academy of Dermatology·Maya ZayourRossitza Lazova
Jan 3, 2013·Pediatric Dermatology·M H ZengQ M Xie
Feb 16, 2021·Journal of the American Academy of Dermatology·Daniele Torchia, Rudolf Happle

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