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Agonist versus antagonist binding to alpha-adrenergic receptors

Proceedings of the National Academy of Sciences of the United States of America

Aug 1, 1980

B B HoffmanJ N Fain

PMID: 6107908

Abstract

The binding properties of two alpha-adrenergic radioligands, [3H]epinephrine (an agonist) and [3H]dihydroergocryptine (an antagonist), were compared in two model systems--membranes derived from human platelets and membranes from rat liver. The platelet contains exclusively alpha 2 and t...read more

Mentioned in this Paper

Ergot Alkaloids, Hydrogenated
Liver
Medihaler-Epi
Alpha-adrenergic receptor
Blood Platelets
Norepinephrine Receptors
Adrenergic alpha-Agonists
Adrenergic alpha-Antagonists
Phosphorylases
Guanylyl Imidodiphosphate
1
7
Paper Details
References
  • References11
  • Citations71
12
  • References11
  • Citations71
12345...

Agonist versus antagonist binding to alpha-adrenergic receptors

Proceedings of the National Academy of Sciences of the United States of America

Aug 1, 1980

B B HoffmanJ N Fain

PMID: 6107908

DOI:

Abstract

The binding properties of two alpha-adrenergic radioligands, [3H]epinephrine (an agonist) and [3H]dihydroergocryptine (an antagonist), were compared in two model systems--membranes derived from human platelets and membranes from rat liver. The platelet contains exclusively alpha 2 and t...read more

Mentioned in this Paper

Ergot Alkaloids, Hydrogenated
Liver
Medihaler-Epi
Alpha-adrenergic receptor
Blood Platelets
Norepinephrine Receptors
Adrenergic alpha-Agonists
Adrenergic alpha-Antagonists
Phosphorylases
Guanylyl Imidodiphosphate
1
7

Related Papers

Paper Details
References
  • References11
  • Citations71
12
  • References11
  • Citations71
12345...
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