Agreement and repeatability of four different devices to measure non-invasive tear breakup time (NIBUT).

Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association
Stefan BandlitzJames S Wolffsohn

Abstract

Since tear film stability can be affected by fluorescein, the Dry Eye Workshop (DEWSII) recommended non-invasive measurement of tear breakup time (NIBUT). The aim of this study was to investigate the agreement and repeatability of four different instruments in the measurement of NIBUT. 72 participants (mean 24.2 ± 3.6 years) were recruited for this multi-centre, cross-sectional study. NIBUT was measured three times from one eye using each of the instruments in randomized order on two separate sessions during a day, separated by at least 2 h. NIBUT was performed at three sites (Switzerland, Germany and UK) using three subjective instruments, Tearscope Plus (Keeler, Windsor, UK) (TS), Polaris (bon Optic, Lübeck, Germany) (POL), EasyTear Viewplus (Easytear, Rovereto, Italy) (ET) and the objective Keratograph 5 M (Oculus Optikgeräte GmbH, Wetzlar, Germany) (KER). As the latter instrument only analyses for 24 s, all data was capped at this value. NIBUT measurements (average of both sessions) between the four instruments were not statistically significantly different: TS (median 10.4, range 2.0-24.0 s), POL (10.1, 1.0-24.0 s), ET (10.6, 1.0-24.0 s) and KER (11.1, 2.6-24.0 s) (p = 0.949). The objective KER measures were on average (1....Continue Reading

Citations

Aug 11, 2020·International Ophthalmology·Ainhoa Molina-MartínDavid P Piñero
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·James S WolffsohnFiona Stapleton
Aug 11, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Carlos Carpena-TorresGonzalo Carracedo

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