PMID: 3321360Nov 1, 1987Paper

AIDS in the pre-AIDS era

Reviews of Infectious Diseases
D HuminerS D Pitlik

Abstract

A search of the medical literature published since 1950 disclosed 19 cases of probable AIDS reported before the start of the current epidemic. These cases retrospectively met the Centers for Disease Control's surveillance definition of the syndrome and had a clinical course suggestive of AIDS. The reports originated from North America, Western Europe, Africa, and the Middle East. The mean age of patients was 37 years, and the ratio of male to female patients was 1.7:1. Sixteen patients had opportunistic infections(s) without Kaposi's sarcoma. The remainder had disseminated Kaposi's sarcoma. The commonest opportunistic infection was Pneumocystis carinii pneumonia. Two patients were reported to be homosexual. Three others had been living in Africa, and one patient was born in Haiti. In two instances concurrent or subsequent opportunistic infection occurred in family members. All patients died 1 month to 6 years after the initial manifestation of disease. In view of the historical data, unrecognized cases of AIDS appear to have occurred sporadically in the pre-AIDS era.

Citations

Jan 1, 1988·Sozial- Und Präventivmedizin·M C Samuel, R R Engel
Jan 1, 1990·Biotherapy·A KarpasB Gazzard
May 1, 1996·Social Science & Medicine·C W Hunt
Jun 1, 1994·Medical Hypotheses·B F Elswood, R B Stricker
Mar 1, 1988·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·D Huminer, S D Pitlik
Dec 13, 1990·Nature·A Karpas

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