PMID: 8945690Oct 1, 1996Paper

AIDS-related Pneumocystis carinii pneumonia in older patients

Journal of General Internal Medicine
S A KeitzR A Weinstein

Abstract

Compared with younger patients, patients aged 50 years or older were less likely to have acquired HIV via intravenous drug use or homosexual contact (p = .0001). Older patients were more likely to have comorbid diseases (12% vs 4%; p = .0001), had more frequent neurologic findings on admission (19% vs 9%; p = .0001), and scored higher on a PCP-specific severity-of-illness scale indicating more severe disease (p = .0001). Older patients had more intensive care unit admissions and intubations (p = .0001). Patients aged 50 years or older were less likely to have a diagnosis of HIV mentioned in their progress notes during the first 2 days of admission (75% vs 85%; p = .0001), less likely to receive PCP-specific therapy within the first 2 hospital days (58% vs 76%; p = .0001), and more likely to receive steroids (32% vs 22%; p = .0001). Older patients had a greater in-hospital mortality (32% vs 18%; p = .0001). However, in logistic regression analysis with mortality as the outcome, the effect of older age was diminished when adjustments were made for insurance status, severity of illness, comorbidity, timely PCP therapy, and inpatient use of steroids. Age differences in mortality for AIDS-related PCP may be explained by increased se...Continue Reading

References

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Citations

Oct 1, 1996·Journal of General Internal Medicine·A C Justice, C Whalen
Mar 21, 1998·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·L A BastianC L Bennett
Jan 11, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John L Perez, Richard D Moore
Jun 2, 2000·AIDS Patient Care and STDs·V Jedlovsky, J K Fleischman
Nov 18, 2006·Drugs & Aging·Kelly A Gebo
Sep 15, 2001·Journal of General Internal Medicine·B KimC L Bennett
Sep 15, 2001·Journal of General Internal Medicine·J Cofrancesco, A W Wu
Jan 7, 1998·Journal of Gerontological Nursing·M R Mueller
Oct 26, 1999·Health Education & Behavior : the Official Publication of the Society for Public Health Education·W E CunninghamR M Andersen
May 17, 2013·Journal of the International Association of Providers of AIDS Care·Camila Lourencini CavellaniLaura Penna Rocha

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