Air pollution and respiratory health among diabetic and non-diabetic subjects in Pune, India-results from the Wellcome Trust Genetic Study

Environmental Science and Pollution Research International
Morteza Abdullatif KhafaieSharad Damodar Gore

Abstract

Diabetics may be more vulnerable to the harmful effects of ambient air pollutants than healthy individuals. But, the risk factors that lead to susceptibility to air pollution in diabetics have not yet been identified. We examined the effect of exposure to ambient PM10 on chronic symptoms and the pulmonary function tests (PFT) in diabetic and non-diabetic subjects. Also, to investigate possible determinants of susceptibility, we recruited 400 type 2 diabetic and 465 healthy subjects who were investigated for chronic respiratory symptoms (CRSs) and then underwent measurement of forced vital capacity (FVC) and forced expiratory volume 1 (FEV1) according to standard protocol. Percent predicted FEV1 and FVC (FEV1% and FVC%, respectively) for each subject were calculated. Particulate matter (PM10) concentrations at residence place of subjects were estimated using AERMOD dispersion model. The association between PM10 and CRSs was explored using logistic regression. We also used linear regression models controlling for potential confounders to study the association between chronic exposure to PM10 and FEV1% and FVC%. Prevalence of current wheezing, allergy symptom, chest tightness, FEV1/FVC <70%, and physician-diagnosed asthma and COPD...Continue Reading

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Citations

Dec 23, 2017·Journal of Exposure Science & Environmental Epidemiology·Morteza Abdullatif KhafaieChittaranjan Sakerlal Yajnik
Oct 27, 2018·Environmental Science and Pollution Research International·Shohreh RabieeMorteza Abdullatif Khafaie
May 10, 2019·International Journal of Environmental Health Research·Rahul Rajak, Aparajita Chattopadhyay
Jul 16, 2019·Multidisciplinary Respiratory Medicine·Morteza A KhafaieBehzad Khafaei
Mar 29, 2018·Environmental Science and Pollution Research International·Mehdi MojadamMorteza Abdullatif Khafaie
Jul 13, 2018·International Journal of Environmental Research and Public Health·Vijay S LimayeDileep Mavalankar
Feb 12, 2021·ERJ Open Research·Jesús Díez-Manglano, Uxua Asìn Samper
Jun 30, 2021·Environmental Pollution·Davi de Ferreyro MonticelliNeyval Costa Reis
Sep 3, 2021·Lung India : Official Organ of Indian Chest Society·Sundeep Santosh SalviArvind Kumar

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