Airflow in Tracheobronchial Tree of Subjects with Tracheal Bronchus Simulated Using CT Image Based Models and CFD Method

Journal of Medical Systems
Shouliang QiJianlin Wu

Abstract

Tracheal Bronchus (TB) is a rare congenital anomaly characterized by the presence of an abnormal bronchus originating from the trachea or main bronchi and directed toward the upper lobe. The airflow pattern in tracheobronchial trees of TB subjects is critical, but has not been systemically studied. This study proposes to simulate the airflow using CT image based models and the computational fluid dynamics (CFD) method. Six TB subjects and three health controls (HC) are included. After the geometric model of tracheobronchial tree is extracted from CT images, the spatial distribution of velocity, wall pressure, wall shear stress (WSS) is obtained through CFD simulation, and the lobar distribution of air, flow pattern and global pressure drop are investigated. Compared with HC subjects, the main bronchus angle of TB subjects and the variation of volume are large, while the cross-sectional growth rate is small. High airflow velocity, wall pressure, and WSS are observed locally at the tracheal bronchus, but the global patterns of these measures are still similar to those of HC. The ratio of airflow into the tracheal bronchus accounts for 6.6-15.6% of the inhaled airflow, decreasing the ratio to the right upper lobe from 15.7-21.4% (...Continue Reading

References

Jan 1, 1995·Journal of Thoracic Imaging·R M MiddletonA L Picone
Apr 17, 2002·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Andrew M Doolittle, Eric A Mair
Nov 12, 2003·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Teresa BerrocalNieves Gómez-León
Nov 23, 2005·Journal of Biomechanics·X L YangH Y Luo
Dec 13, 2005·Journal of Pediatric Surgery·Nobuyuki MorikawaMorihiro Saeki
Nov 15, 2006·Journal of Pediatric Surgery·Takahiko SeoAtsuo Itakura
May 15, 2007·Journal of Biomechanics·H Y LuoX L Yang
Oct 3, 2007·Pediatric Radiology·Zhu Ming, Zhang Lin
Dec 22, 2007·Medical Engineering & Physics·J W De BackerW De Backer
May 27, 2008·Journal of Biomechanics·T GemciR Collins
Jul 11, 2008·Journal of Biomechanics·Rainhill K Freitas, Wolfgang Schröder
Aug 1, 2008·Journal of Biomechanics·H Y Luo, Y Liu
Jan 13, 2009·Pediatric Pulmonology·Serena PanigadaGiovanni A Rossi
Mar 3, 2009·Radiologic Clinics of North America·Amandine Desir, Benoît Ghaye
May 22, 2009·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·Ching-Long LinEric A Hoffman
Jun 9, 2009·Journal of Biomechanics·Goutham MylavarapuEphraim Gutmark
Jul 25, 2009·Allergology International : Official Journal of the Japanese Society of Allergology·Yasutaka NakanoTaishi Nagao
Nov 19, 2010·Radiology·Jan W De BackerWilfried De Backer
Dec 17, 2010·World Journal of Radiology·Archana T LaroiaEdwin van Beek
Jul 20, 2011·IEEE Transactions on Bio-medical Engineering·D Keith WaltersRobert L Hester
Jan 10, 2012·Respiratory Care·Gregg L Ruppel, Paul L Enright
Dec 6, 2012·Experimental Hematology & Oncology·Chien-Yi HoTzu-Ching Shih
Jan 30, 2013·The Journal of Pediatrics·Lauren S MottUNKNOWN Australian Respiratory Early Surveillance Team for Cystic Fibrosis Study Group
Jul 25, 2014·Computers in Biology and Medicine·Bora SulVineet Rakesh
Jul 12, 2016·Radiographics : a Review Publication of the Radiological Society of North America, Inc·G ChassagnonD Sirinelli
Jan 16, 2018·Computational and Mathematical Methods in Medicine·Shouliang QiWei Qian

❮ Previous
Next ❯

Citations

Jun 2, 2018·International Journal for Numerical Methods in Biomedical Engineering·Minsuok KimYongmann M Chung
Aug 30, 2018·BioMed Research International·Baihua ZhangJianlin Wu
Oct 5, 2019·Respiratory Physiology & Neurobiology·Daniel S HariprasadAnders Wallqvist
Apr 8, 2021·International Journal for Numerical Methods in Biomedical Engineering·Marta TullioAndrea Aliverti

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.