PMID: 18710089Aug 20, 2008Paper

Airplane headaches--two new cases and a review of the literature

Acta Medica Croatica : C̆asopis Hravatske Akademije Medicinskih Znanosti
Marina Titlić, Vida Demarin

Abstract

We present two new cases of airplane headache and compare them with 13 cases described so far. The two new cases refer to a man and a woman, one each. The woman suffered from headache during the take off and throughout the flight, which is rarely encountered. The man had a typical airplane headache with accompanying symptoms, with the feeling of pressure in the left side of the head. Diagnostic treatment revealed no pathomorphological substrate of the condition. The etiology and pathophysiology of this type of headache have not yet been fully clarified. We presume that this type of headache may be connected with changes in the nasal mucous membrane with deviation of the nasal septum, as well as in ethmoidal sinuses and other paranasal cavities. The rise of atmospheric pressure in the airplane and barotrauma from activation of the trigeminovascular system certainly play a major role in the occurrence of this headache.

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