PMID: 1201469Nov 1, 1975Paper

Airway closure in pregnancy

Canadian Anaesthetists' Society Journal
D B Craig, M A Toole

Abstract

Closing capacity (CC; the lung volume at which dependent lung zones cease to ventilate, presumably as a result of airway closure) and standard lung volumes were measured in twenty-four normal women 21 to 29 years of age in the seated and supine positions. Measurements were made serially during pregnancy and once 6 to 8 weeks post partum (the control period). CC was unchanged during pregnancy, while functional residual capacity (FRC) fell by approximately 15%. The difference between FRC and CC (FRC-CC) was reduced during pregnancy, but in one of the subjects when seated, and in only two supine subjects did CC exceed FRC. FRC-CC was reduced in the supine position as compared to seated. The reduced FRC-CC during pregnancy offers a potential explanation for the observations of abnormally low arterial oxygen tensions (Pao2) during pregnancy in some women, and of reduced Pao2 in pregnant women in the supine as compared to upright position.

References

Jan 5, 1974·British Medical Journal·D R BevanM K Sykes
Nov 1, 1971·Journal of Applied Physiology·D B CraigM R Becklake
Oct 25, 1969·British Medical Journal·C K AngC Wood
Apr 1, 1970·The Journal of Obstetrics and Gynaecology of the British Commonwealth·G J Andersen, J Walker
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Jul 1, 1965·Anesthesiology·C M PROWSE, E A GAENSLER

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Citations

Nov 1, 1996·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R M Wahba
Mar 1, 1996·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·V ShulmanM R Bye
Nov 1, 1989·Respiratory Medicine·O NørregaardR Dahl
Aug 24, 2004·International Journal of Obstetric Anesthesia·B ChironC Mercier
Jun 1, 1977·Anaesthesia·A HoldcroftM K Sykes
May 1, 1979·Postgraduate Medical Journal·J A Milne
May 31, 2002·Thorax·N EdwardsC E Sullivan
Aug 1, 1978·Thorax·G S GarrardC W Redman
Nov 2, 2002·American Journal of Respiratory and Critical Care Medicine·Bilgay IzciNeil J Douglas
Jun 1, 1977·British Journal of Obstetrics and Gynaecology·J A MilneA I Pack
Feb 1, 2011·Clinics in Chest Medicine·Matthew J Hegewald, Robert O Crapo
Dec 14, 2011·Respiratory Physiology & Neurobiology·Johannes SchramelYves Moens
Dec 7, 2007·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Dennis JensenDenis E O'Donnell

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