Airway dimensions at inspiratory and expiratory multisection CT in chronic obstructive pulmonary disease: correlation with airflow limitation

Radiology
Shin MatsuokaYasuo Nakajima

Abstract

To analyze the relationship between airflow limitation and airway dimensions from the third to the fifth generation of bronchi in patients with chronic obstructive pulmonary disease (COPD) by using inspiratory and expiratory multisection computed tomography (CT). This retrospective study was approved by the institutional review board, which waived the need for informed consent. The study included 50 patients with COPD who underwent both inspiratory and expiratory 64-detector CT. In each patient, mean values of airway luminal areas from the third to the fifth generation of three bronchi (right B1, right B10, and left B3) were measured at inspiratory CT (IA3, IA4, and IA5) and expiratory CT (EA3, EA4, and EA5). To evaluate the change of the airway luminal area between inspiration and expiration, the ratio of expiratory to inspiratory airway luminal area in each generation was calculated (EA3/IA3, EA4/IA4, and EA5/IA5). Correlations between airway dimensions and pulmonary function test results were evaluated. The correlation coefficients between airway luminal area measured at expiratory CT and the forced expiratory volume in 1 second (FEV(1)) were higher than those for inspiratory CT and improved as the airway size decreased from...Continue Reading

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Citations

Mar 27, 2010·Journal of Anesthesia·Gaëlle MourissouxMarc Fischler
Oct 2, 2012·Respiratory Investigation·Nguyen Van ThoYasutaka Nakano
Aug 26, 2009·Journal of Thoracic Imaging·Shin MatsuokaHiroto Hatabu
Sep 3, 2011·Respirology : Official Journal of the Asian Pacific Society of Respirology·Kazuyoshi KurashimaYutaka Sugita
Jan 18, 2012·Respirology : Official Journal of the Asian Pacific Society of Respirology·Makoto Hoshino, Junichi Ohtawa
Oct 15, 2011·American Journal of Respiratory and Critical Care Medicine·Hiroki NishineTeruomi Miyazawa
Jan 14, 2009·Proceedings of the American Thoracic Society·Harvey O Coxson
Nov 10, 2013·International Journal of Chronic Obstructive Pulmonary Disease·Kazuyoshi KurashimaYoshinori Kawabata
Nov 19, 2010·Radiology·Jan W De BackerWilfried De Backer
Sep 24, 2014·AJR. American Journal of Roentgenology·Xueqian XieHarry J M Groen
Jan 20, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Shin MatsuokaHiroto Hatabu
Jun 15, 2013·Respiratory Medicine·K Konstantinos KatsoulisTheodore Kontakiotis
May 19, 2010·Respiratory Physiology & Neurobiology·Plamen BokovChristophe Delclaux
Oct 8, 2015·European Journal of Radiology·Thitiporn SuwatanapongchedSumalee Kiatboonsri
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Jul 25, 2009·Allergology International : Official Journal of the Japanese Society of Allergology·Yasutaka NakanoTaishi Nagao

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