Airway eicosanoids in acute severe respiratory syncytial virus bronchiolitis

The Journal of Pediatrics
Yves SznajerBaruch Joseph Toledano

Abstract

We prospectively studied the levels of eicosanoids in intubated patients with severe bronchiolitis and compared them to electively intubated non-infected infants. LeukotrieneE(4) (LTE(4)), leukotrieneB(4) (LTB(4)), and prostaglandinE(2) (PGE(2)) levels were significantly increased (P <.01) from endotracheal (ET) aspirates of infants with bronchiolitis compared with controls, as were urinary LTE(4) levels (P <.001). We conclude that eicosanoids are increased in the tracheal aspirates and urine of children with bronchiolitis.

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Citations

Nov 7, 2007·Clinical Reviews in Allergy & Immunology·Robert C Welliver
Aug 9, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Hiroto MatsuseShigeru Kohno
Jun 6, 2012·Mediators of Inflammation·Mary K McCarthy, Jason B Weinberg
Nov 3, 2011·Experimental Lung Research·Kim M GriggsDani-Louise Dixon
Mar 7, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Liviana Da DaltEugenio Baraldi
Oct 8, 2005·The Journal of Allergy and Clinical Immunology·Sigurdur KristjanssonIngileif Jonsdottir
Jul 13, 2005·Pediatric Clinics of North America·Susan E Coffin
Mar 4, 2014·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Linda KortzUta Ceglarek
May 3, 2005·Current Opinion in Infectious Diseases·Asunción MejíasOctavio Ramilo
Apr 14, 2010·Pediatric Emergency Care·Frank D Petruzella, Marc H Gorelick
Aug 18, 2005·Pediatric Pulmonology·Giovanni PiedimonteRenato Cutrera
Jan 19, 2020·Science Immunology·Saltanat UaliyevaLora G Bankova
Jul 31, 2020·Viruses·Ismail Sebina, Simon Phipps
Oct 31, 2020·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Elizabeth A SellNoam A Cohen
Nov 11, 2019·Veterinary Immunology and Immunopathology·Amelia R Hofstetter, Randy E Sacco
May 11, 2021·Frontiers in Medicine·Heloísa Antoniella Braz-de-MeloKelly Grace Magalhães

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