Airway symptoms and sleeping difficulties in operated and non-operated patients with gastroesophageal reflux disease

Scandinavian Journal of Gastroenterology
Rune JohannessenPer Martin Kleveland

Abstract

Anti-reflux treatment studies have not succeeded in proving a causal relationship between gastroesophageal reflux disease (GERD), airway symptoms and sleeping difficulties. In a recent follow-up study we showed that patients operated for GERD have significantly less heartburn/acid regurgitation symptoms than matched non-operated patients. These two groups probably had different degrees of reflux over a long period of time. It is thus hypothesized that operated patients would report less airway symptoms and sleeping difficulties than comparable non-operated patients. A new follow-up study of the same patients was therefore conducted. A total of 179 patients operated for GERD and 179 matched non-operated patients with confirmed GERD were sent the Reflux, Airway & Sleep Questionnaire (RASQ), which is a new, validated questionnaire dealing with heartburn/acid regurgitation, airway symptoms, and sleeping difficulties. Answers are given on a 7-point Likert scale and the assessment period is 1 year. Response rates were 68% in both groups. Operated patients reported significantly less reflux symptoms than non-operated patients (p < 0.001). Patients in the surgery group also reported less symptoms in two subscales of the RASQ dealing wi...Continue Reading

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Citations

Mar 5, 2013·Gastroenterology Clinics of North America·Yasuhiro FujiwaraRonnie Fass
Jun 22, 2016·Journal of Gastroenterology·Katsuhiko IwakiriTooru Shimosegawa
May 17, 2017·World Journal of Surgery·Feroze SidwaP Marco Fisichella
May 18, 2020·The Lancet. Gastroenterology & Hepatology·William C OrrAnn O Scheimann
Aug 3, 2021·Current Gastroenterology Reports·Michael KurinRonnie Fass

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