PMID: 11334196May 4, 2001Paper

Albumin in the pump prime: its effect on postoperative weight gain

Perfusion
D L ZarroT G Phillips

Abstract

An investigation was conducted to determine whether adding albumin to the prime of the cardiopulmonary bypass circuit had any effect on postoperative weight gain. Patients undergoing non-emergency myocardial revascularization for coronary artery disease were divided into two groups. Group I (albumin) received 250 ml of 5% human albumin in their pump prime, whereas group II (control) served as controls. The same surgeon, anesthesia technique, perfusion circuit and conduct, and postoperative management were employed for all patients in the study. No statistically significant differences could be found between the groups for any of the variables studied, including fluid intake during surgery and the first 24 h postoperation, urine output, fluid balance and postoperative weight gain. The authors conclude from this investigation that adding 250 ml of 5% human albumin to the pump prime has no effect on postoperative weight gain. The next step could be to examine the effect of using larger amounts of albumin or plasma volume expanders in the pump prime.

References

Jul 1, 1989·Critical Care Medicine·T E Emerson
Dec 1, 1982·The Annals of Thoracic Surgery·J T DiehlD M Cosgrove
Dec 1, 1982·The Annals of Thoracic Surgery·D A PalanzoJ A Waldhausen
Jul 20, 1999·Perfusion·D A PalanzoN J Manley
Jul 1, 1960·Circulation Research·P F SALISBURYP A RIEBEN

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Citations

Sep 15, 2004·Journal of Cardiothoracic and Vascular Anesthesia·James A RussellMahlon M Wilkes
Aug 4, 2005·The Journal of Thoracic and Cardiovascular Surgery·Marit FarstadPaul Husby
May 15, 2012·The Journal of Thoracic and Cardiovascular Surgery·Roberta J NavickisMahlon M Wilkes
Sep 25, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Kun YuCun Long
Apr 22, 2003·The International Journal of Artificial Organs·F OnoratiM Cotrufo

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