Albuminuria during the screening for diabetes in a semi-rural area (Kisantu City, DR Congo)

Néphrologie & thérapeutique
Rissassi MakuloErik Muls

Abstract

To determine the prevalence of microalbuminuria, macroalbuminuria and renal insufficiency at the time of screening for diabetes and impaired fasting glucose in the semi-rural area of Kisantu/DR Congo, and to identify determinants of pathological urinary albumin excretion (UAE). Step 1: diabetes (81 cases) and impaired fasting glucose (148 cases) tracking in the population (1898 subjects selected by a systematic survey). Step 2: urinary albumin and serum creatinine were measured and glomerular filtration rate was estimated (modification of the diet in renal disease [MDRD] equation). The determinants of pathological UAE were assessed by logistic regression. The prevalence of macroalbuminuria and microalbuminuria in diabetes was 12.0 and 45.2% respectively versus 0 and 13.7% in impaired fasting glucose. Determinants of pathological UAE were: diabetes (adjusted OR [aOR]: 7.01; 95% CI: 3.48-14.11), central obesity (aOR: 2.36 [1.16-4.80]), age less that 60 years (aOR: 2.12 [1.05-4.40]), hypertension [aOR: 3.30 (1.39-7.82)] and diabetic retinopathy (aOR: 3.12 [1.54-6.26]). Renal insufficiency (MDRD<60ml/min/1.73m(2)) prevalence was 21.4% in diabetes and 3.8% in impaired fasting glucose. Microalbuminuria and macroalbuminuria are freque...Continue Reading

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Citations

May 10, 2017·Tropical Medicine and Health·Jacques Lofandjola MasumbukuJean Petermans
Aug 2, 2019·African Journal of Primary Health Care & Family Medicine·Shomba L RitaLukanu P Ngwala

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