Alcohol affects otolith-induced ocular counterrolling: dosage effects

Acta Oto-laryngologica
Shirley G Diamond, Charles H Markham

Abstract

Otolith function is significantly affected by alcohol ingestion and the higher the dosage, the greater the effect. To determine how the effect of a 5 oz (150 ml) dose of alcohol differs from an earlier study examining the effect of 3 oz (90 ml) on ocular counterrolling (OCR). Twenty subjects underwent OCR testing before and after drinking 5 oz of 80 proof vodka. Blood alcohol levels (BAL) of the subjects ranged from 0.09 to 0.18%. Three measures of OCR were considered. Amplitude was significantly reduced post-alcohol; disconjugacy was significantly increased post-alcohol; smoothness was not significantly different pre- and post-alcohol. In contrast, the lower 3 oz study produced BAL of 0.04-0.09% and resulted in significantly reduced OCR amplitude, no significant change in disconjugacy, but a significant improvement in smoothness. The increase in BAL produced further impairment of amplitude and conjugacy but eliminated the benefit of smoothness.

References

Feb 8, 1974·Nature·K E Money, W S Myles
Mar 21, 1998·Acta Oto-laryngologica·N Furuya, T Koizumi
Jun 18, 1999·Annals of the New York Academy of Sciences·Y UchinoN Isu
Jan 24, 2002·Vision Research·J H CabungcalB J M Hess
Jan 1, 1958·Acta Oto-laryngologica. Supplementum·G ASCHAN
Oct 27, 2004·Proceedings of the National Academy of Sciences of the United States of America·Gay R HolsteinStephen M Highstein
Feb 8, 2005·Nature Neuroscience·H Jacob HancharMartin Wallner
Feb 17, 2005·Progress in Neurobiology·Catherine M GliddonPaul F Smith
Jan 24, 2006·Pharmacology & Therapeutics·J L Weiner, C F Valenzuela
Jul 4, 2006·Pharmacology & Therapeutics·Martin WallnerRichard W Olsen

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Citations

Jan 21, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Sally M RosengrenThomas N Roth
Aug 20, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Giovanni Mostile, Joseph Jankovic

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