Alcohol and breast cancer risk defined by estrogen and progesterone receptor status: a case-control study

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Silvia DeandreaEva Negri

Abstract

Alcohol consumption increases breast cancer risk. Some studies suggested that this association is stronger or limited to tumors expressing estrogen receptors (ER). We investigated the role of alcohol according to ER and progesterone receptor (PR) status in a case-control study on breast cancer conducted from 1991 to 1994 in three Italian areas. Cases were 989 women with incident, histologically confirmed breast cancer. Controls were 1,350 women admitted to hospitals in the same catchment areas for acute nonneoplastic diseases. A validated food-frequency questionnaire was used to collect information on dietary habits and lifetime consumption of various alcoholic beverages. Multiple logistic regression models were used to estimate odds ratios and 95% confidence interval (95% CI). Alcohol drinking was associated with ER+ tumors (odds ratio, 2.16; 95% CI, 1.68-2.76 for an intake of > or =13.8 g/d as compared with nondrinkers). The odds ratio was 1.13 (95% CI, 1.07-1.20) for a 10-g increase in daily intake. For ER- tumors, the relation with alcohol consumption was not significant (odds ratio, 1.36; 95% CI, 0.93-2.01). When breast cancers were further classified according to PR, the findings for ER+PR+ cancers were similar to those f...Continue Reading

References

Jul 1, 1986·American Journal of Epidemiology·W Willett, M J Stampfer
Dec 1, 1994·American Journal of Epidemiology·P C NascaB B Metzger
May 18, 1996·Lancet·S FranceschiA Giacosa
Aug 1, 1996·International Journal of Epidemiology·M FerraroniS Salvini
Dec 16, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M FerraroniC La Vecchia
Mar 31, 1999·British Journal of Cancer·S M EngerL Bernstein
Feb 5, 2004·Journal of the National Cancer Institute·Graham A ColditzSusan E Hankinson
Aug 2, 2005·Alcohol·Ramona G Dumitrescu, Peter G Shields
Oct 19, 2005·Annals of Epidemiology·Mary Beth TerryMarilie D Gammon
Dec 14, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Lena U RosenbergCecilia Magnusson
Jan 6, 2007·American Journal of Epidemiology·Shumin M ZhangJulie E Buring

❮ Previous
Next ❯

Citations

Nov 3, 2011·JAMA : the Journal of the American Medical Association·Wendy Y ChenWalter C Willett
Feb 21, 2013·Women & Health·Lee WangChung-Chin Yao
Mar 31, 2012·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Helmut K SeitzCarlo La Vecchia
Oct 12, 2012·Carcinogenesis·Qingsong ZhangShuping Zhong
Jan 7, 2009·Current Opinion in Obstetrics & Gynecology·Marie Lof, Elisabete Weiderpass
Nov 15, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Marilyn L KwanBette J Caan
Sep 2, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Marilyn L KwanBette J Caan
Aug 29, 2013·Future Oncology·Chiara ScocciantiIsabelle Romieu
Sep 10, 2014·International Journal of Food Sciences and Nutrition·Niki MouroutiDemosthenes B Panagiotakos
Feb 12, 2014·American Journal of Preventive Medicine·Chiara ScocciantiIsabelle Romieu
May 7, 2013·The Breast : Official Journal of the European Society of Mastology·Valentina RosatoCarlo La Vecchia
Dec 3, 2014·Critical Reviews in Oncology/hematology·Sohiya Yotsukura, Hiroshi Mamitsuka
Oct 5, 2016·Gene·Ganggang Shi, Shuping Zhong
Aug 3, 2011·Cadernos de saúde pública·Lívia Emi InumaruMaria Margareth Veloso Naves
Nov 30, 2019·Oxidative Medicine and Cellular Longevity·Chenghao HuangShuping Zhong
Oct 5, 2019·Oncology Reviews·Luis Mendoza
Jan 7, 2009·Current Opinion in Obstetrics & Gynecology

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.