Abstract
Overdose from alcohol and/or drugs kills tens of thousands of Americans annually, with a large number of deaths attributed to opioid pain medications. Addiction treatment patients are known to be at high risk for overdose; however, the relationship between pain and overdose history within this group is understudied, especially in relation to alcohol overdoses. In the present study, we evaluated whether nonfatal overdose history was more likely among addiction treatment patients with pain, and examined the characteristics of overdoses among those with and without pain. We analyzed cross-sectional data from 739 patients at a large residential addiction treatment center (median age 37, 25.7% female). We used 2-stepped binary regression models to evaluate whether demographics, pain type (chronic, acute, or both), depression symptoms, and opioid misuse were associated with lifetime history of nonfatal (1) alcohol and (2) drug overdose (lifetime yes/no), and conducted follow-up analyses examining overdose characteristics. In adjusted analyses, history of chronic pain (odds ratio [OR] 2.60, 95% confidence interval [CI] 1.59, 4.27) and illicit drug use (OR 1.99, 95% CI 1.07, 3.68) were associated with an increased likelihood of nonfata...Continue Reading
References
Jan 1, 1980·The Journal of Nervous and Mental Disease·A T McLellanC P O'Brien
Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
May 15, 2003·JAMA : the Journal of the American Medical Association·Andrew RosenblumRussell K Portenoy
Dec 23, 2003·Drug and Alcohol Dependence·Jodie A TraftonKeith Humphreys
Jul 9, 2005·Drug and Alcohol Dependence·Melissa TracySandro Galea
May 12, 2007·Pain·Stephen F ButlerRobert N Jamison
Apr 9, 2008·The American Journal on Addictions·Jennifer Sharpe PotterRoger D Weiss
Jul 19, 2008·Addiction·Jeffrey H SametEdwin E Zvartau
Oct 16, 2008·Addiction·Ryan M CaldeiroAndrew J Saxon
Feb 13, 2009·Expert Review of Neurotherapeutics·Shelley Wiechman AskayDavid R Patterson
May 28, 2009·Addiction·Jeffrey H Samet, Alexander Y Walley
Oct 16, 2009·Drug and Alcohol Dependence·Peter C BrittonKenneth R Conner
Apr 16, 2011·Journal of Substance Abuse Treatment·Amanda M PriceAmy S B Bohnert
Jun 15, 2011·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Penny L BrennanRudolf H Moos
May 4, 2013·Journal of Aging and Health·Penny L Brennan, Sonya Soohoo
Dec 10, 2013·The American Journal on Addictions·Erin E BonarAmy S B Bohnert
Mar 25, 2015·Journal of Substance Abuse Treatment·Lisham AshrafiounMark A Ilgen
Jun 23, 2015·Journal of Studies on Alcohol and Drugs·Andrzej JakubczykMarcin Wojnar
Jul 28, 2015·Arthritis Care & Research·Gary J Macfarlane, Marcus Beasley
Dec 15, 2015·Drug and Alcohol Dependence·A JakubczykM Wojnar
Jan 27, 2016·Journal of General Internal Medicine·Daniel P AlfordRichard Saitz
Feb 3, 2016·Pain·Chad M BrummettAfton L Hassett
Feb 18, 2016·Addiction·Mark A IlgenFrederic C Blow
Mar 20, 2016·Drug and Alcohol Dependence·Alexander CaudarellaKanna Hayashi
Apr 12, 2016·Drug and Alcohol Dependence·Amy S B BohnertMaureen Walton
Dec 30, 2016·MMWR. Morbidity and Mortality Weekly Report·Rose A RuddLawrence Scholl
Apr 14, 2017·JAMA Surgery·Chad M BrummettBrahmajee K Nallamothu
Jan 10, 2018·Alcoholism, Clinical and Experimental Research·Katie Witkiewitz, Kevin E Vowles
Citations
Mar 18, 2020·JAMA Network Open·Kevin R RiggsStefan G Kertesz
Jul 18, 2019·Harm Reduction Journal·Rachel E GicquelaisAmy S B Bohnert
Jun 13, 2020·The American Journal of Drug and Alcohol Abuse·Victoria R VotawR Kathryn McHugh
Jul 22, 2020·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·Rachel E GicquelaisAnne C Fernandez
Nov 20, 2020·BMC Public Health·Francisco A Montiel IshinoFaustine Williams
Aug 28, 2021·Pharmacy : Journal of Pharmacy, Education and Practice·M Aryana BryanGerald Cochran