Alcohol and Opioid Use in Chronic Pain: A Cross-Sectional Examination of Differences in Functioning Based on Misuse Status

The Journal of Pain : Official Journal of the American Pain Society
Kevin E VowlesMark D Sullivan

Abstract

Opioid misuse is regularly associated with disrupted functioning in those with chronic pain. Less work has examined whether alcohol misuse may also interfere with functioning. This study examined frequency of opioid and alcohol misuse in 131 individuals (61.1% female) prescribed opioids for the treatment of chronic pain. Participants completed an anonymous survey online, consisting of measures of pain, functioning, and opioid and alcohol misuse. Cut scores were used to categorize individuals according to substance misuse status. Individuals were categorized as follows: 35.9% (n = 47) were not misusing either opioids or alcohol, 22.9% (n = 30) were misusing both opioids and alcohol, 38.2% (n = 50) were misusing opioids alone, and only 3.0% (n = 4) were misusing alcohol alone. A multivariate analysis of variance was performed to examine differences in pain and functioning between groups (after excluding individuals in the alcohol misuse group due to the small sample size). Group comparisons indicated that individuals who were not misusing either substance were less disabled and distressed in comparison to those who were misusing opioids alone or both opioids and alcohol. No differences were indicated between the latter 2 groups. ...Continue Reading

Citations

Dec 17, 2019·Alcoholism, Clinical and Experimental Research·Scott EdwardsKatie Witkiewitz
Feb 28, 2020·Expert Opinion on Pharmacotherapy·Lauren E HoodM Foster Olive
Apr 25, 2020·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Asimina LazaridouChristopher Gilligan
Aug 10, 2020·Journal of Neuroscience Research·Jesús David LorenteLucía Hipólito
Nov 5, 2020·Drug and Alcohol Dependence·Steven J NietoLara A Ray
Feb 20, 2021·Biochemistry·Minji JeonAvi Ma'ayan
Jun 25, 2021·World Journal of Gastroenterology : WJG·Ishani ShahDarshan J Kothari
Jul 20, 2021·Neuroscience Letters·Jessica A Cucinello-RaglandScott Edwards
Jan 14, 2022·European Journal of Drug Metabolism and Pharmacokinetics·Gerd JakobssonRobert Kronstrand

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