PMID: 5303551Dec 14, 1968Paper

Alcohol, aspirin, and gastrointestinal bleeding

British Medical Journal
K Goulston, A R Cooke

Abstract

In 20 healthy male subjects faecal blood loss was measured by means of a chromium-51-labelled red blood cell technique. Mean daily faecal blood loss associated with unbuffered aspirin ingestion was significantly increased by alcohol in the 13 subjects studied. In seven others alcohol alone did not cause gastrointestinal bleeding. These findings suggest that alcohol may accentuate gastrointestinal blood loss associated with unbuffered aspirin ingestion.

Citations

Apr 1, 1975·Journal of Clinical Pharmacology·A ArsenaultA Lussier
Nov 1, 1976·The American Journal of Digestive Diseases·W H MetzgerP H Guth
Mar 1, 1973·The American Journal of Digestive Diseases·A R Cooke
Feb 1, 1975·The American Journal of Digestive Diseases·K Kawashima, G B Jerzy Glass
Jan 1, 1978·The American Journal of Digestive Diseases·D Y Graham, R E Davis
Nov 1, 1982·Digestive Diseases and Sciences·K Y YikW C Watson
May 1, 1988·Digestive Diseases and Sciences·M M CohenH R Wang
Oct 1, 1975·Agents and Actions·K D Rainsford
Sep 1, 1970·The American Journal of Digestive Diseases·V P DinosoS H Lorber
Jan 1, 1979·European Journal of Drug Metabolism and Pharmacokinetics·J D GuptaW Ablett
Jan 1, 1987·Pharmacology & Therapeutics·R O DayJ de Jager
Mar 1, 1990·Alcohol·D P MikhailidisJ Y Jeremy
Aug 23, 1980·Lancet·W D Rees, L A Turnberg
Sep 23, 1971·The New England Journal of Medicine·B M SmithW Silen
May 30, 1985·The New England Journal of Medicine·D A AhlquistR A Owen
Jan 1, 1976·Australian and New Zealand Journal of Medicine·A R Cooke
Aug 9, 1969·British Medical Journal·A R Cooke, K Goulston
Oct 1, 1971·Gut·C D NeedhamD F Kerridge
Apr 1, 1970·Postgraduate Medical Journal·S Goulston, K Breen
May 23, 1970·British Medical Journal
Jun 1, 1975·CRC Critical Reviews in Toxicology·D J John
Jan 26, 2008·Clinical Therapeutics·Elliot V HershPaul A Moore
Jul 1, 1972·Seminars in Nuclear Medicine·B I Friedman
Nov 14, 1983·The American Journal of Medicine·L F Prescott, J A Critchley
Nov 14, 1983·The American Journal of Medicine·U Klotz
Nov 1, 1982·Journal of the American Geriatrics Society·P P Gerbino
Jul 5, 1974·Nature·J C ManglaA A Rubulis
Apr 1, 1973·The British Journal of Surgery·M M HegartyP F Schofield
Dec 1, 1977·Australian and New Zealand Journal of Medicine·G B HoweG G Graham
Sep 1, 1970·Arthritis and Rheumatism
May 1, 1970·Australasian Annals of Medicine·A R Cooke
May 1, 1983·Acta Pharmacologica Et Toxicologica·J PuurunenJ Hirvonen
Sep 1, 1989·Journal of Gastroenterology and Hepatology·K Satake
Mar 1, 1989·Medical Toxicology and Adverse Drug Experience·S SzaboK D Rainsford
Aug 1, 1970·Australasian Annals of Medicine·A R Cooke

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