Alcohol Consumption and Functional Limitations in Older Men: Does Muscle Strength Mediate Them?

Journal of the American Geriatrics Society
Tong WangYili Wu

Abstract

To evaluate the dose-response relationships between alcohol consumption and functional limitations in older European men, and explore the role of muscle strength as a mediator of these relationships. Cross-sectional study of older men participating in the Survey of Health, Aging and Retirement in Europe (SHARE). Urban and rural households in 17 European countries and Israel. A total of 17 870 men aged 65 years and older from the SHARE (Wave 6, 2015) were included in this study. Outcome variables were functional limitations: mobility limitation, arm function limitation, and fine motor limitation. Main exposure variable was alcohol consumption. Mediating factor was grip strength. Basic demographics, life habits, and health status were considered as potential confounders. Dose-response analyses with restricted cubic splines and the Karlson/Holm/Breen method were conducted. A total of 17 870 participants were included in this study. Dose-response analyses revealed that moderate alcohol consumption was related to the lower odds of reporting mobility limitation (≤35 units/wk) and arm function limitation (≤41 units/wk), with a minimum odds ratio (OR) occurring at 10 units/week drinks for mobility limitation (OR = .71; 95% confidence i...Continue Reading

References

Oct 26, 1999·The British Journal of Psychiatry : the Journal of Mental Science·M J PrinceJ R Copeland
Apr 23, 2005·Journal of Clinical Epidemiology·Tiina-Mari LyyraEino Heikkinen
Feb 17, 2007·Journal of the American Geriatrics Society·Peggy M CawthonUNKNOWN Osteoporotic Fractures in Men Research Group
Oct 4, 2007·Journal of the American Geriatrics Society·John T Chang, David A Ganz
Aug 5, 2008·International Journal of Epidemiology·Teresa Bago d'UvaEddy van Doorslaer
Sep 10, 2009·Journal of the American Geriatrics Society·Cinzia MaraldiUNKNOWN Health ABC study
Oct 24, 2009·Neuroscience and Biobehavioral Reviews·Rachael D SeidlerDavid B Lipps
Jan 21, 2010·Statistics in Medicine·Loic Desquilbet, François Mariotti
May 21, 2013·Alcoholism, Clinical and Experimental Research·Timothy C DurazzoDieter J Meyerhoff
Jun 20, 2013·International Journal of Epidemiology·Axel Börsch-SupanUNKNOWN SHARE Central Coordination Team
Sep 21, 2013·Current Pharmaceutical Design·Yuri Milaneschi, Brenda W J H Penninx
Aug 25, 2015·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Rosario OrtoláFernando Rodríguez-Artalejo
Sep 13, 2015·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Vincentius J A VerlindenM Arfan Ikram
Jun 4, 2016·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Luz Ma León-MuñozFernando Rodríguez-Artalejo
Oct 21, 2016·Alcoholism, Clinical and Experimental Research·Adam J WoodsRonald A Cohen
Aug 11, 2009·European Journal of Ageing·Karen Andersen-RanbergK Christensen
Apr 6, 2018·Gerontology & Geriatric Medicine·Heidi D NelsonTeresa A Hillier
Oct 26, 2018·Journal of the American Geriatrics Society·Tong WangQihua Tan

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.