Alcohol consumption and heart failure in hypertensive US male physicians.

The American Journal of Cardiology
Luc Djoussé, J Michael Gaziano

Abstract

Although alcohol drinking increases blood pressure and heavy drinking has been associated with alcoholic cardiomyopathy, little is known about the association between light to moderate drinking and risk of heart failure (HF) in hypertensive subjects. Thus, the association between light to moderate drinking and incident HF in 5,153 hypertensive male physicians who were free of stroke, myocardial infarction, or major cancers at baseline was prospectively examined. Alcohol consumption was self-reported and classified as <1, 1 to 4, 5 to 7, and >or=8 drinks/week. HF was ascertained using follow-up questionnaires and validated using Framingham criteria. Average age was 58 years, and about 70% of subjects consumed 1 to 7 drinks/week. A total of 478 incident HF cases occurred in this cohort during follow-up. Compared with subjects consuming <1 drink/week, hazard ratios for HF were 0.89 (95% confidence interval [CI] 0.70 to 1.12), 0.72 (95% CI 0.57 to 0.91), and 0.38 (95% CI 0.20 to 0.72) for alcohol consumption of 1 to 4, 5 to 7, and >or=8 drinks/week after adjustment for age, body mass index, smoking, randomization group, use of multivitamins, vegetable consumption, breakfast cereal, exercise, and history of atrial fibrillation, resp...Continue Reading

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Citations

Jul 16, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Paloma Gil-BernabeYoshiyuki Takei
Sep 8, 2012·ISRN Cardiology·Javed Butler
Jul 30, 2011·Clinical and Experimental Hypertension : CHE·Mingliang GuWenquan Niu
Feb 18, 2012·International Journal of Cardiology·Rajesh Movva, Vincent M Figueredo
Jan 30, 2010·Progress in Cardiovascular Diseases·Eric H Awtry, George J Philippides
Nov 17, 2015·International Journal of Cardiology·Katalin GémesKenneth J Mukamal
Apr 2, 2009·European Journal of Heart Failure·Irma LaonigroEmanuele Altomare
Mar 23, 2012·Nursing & Health Sciences·Oksoo KimHae Ok Jeon
Sep 17, 2013·Alcoholism, Clinical and Experimental Research·Elia C El HajjJason D Gardner
Feb 14, 2014·Journal of Neurochemistry·Inna I Kruman, Anna-Kate Fowler
Mar 4, 2014·Mayo Clinic Proceedings·James H O'KeefeCarl J Lavie
Jun 24, 2015·Nature Reviews. Cardiology·Joaquim Fernández-Solà
Mar 1, 2018·Frontiers in Pharmacology·Adam ObadSima T Tarzami
Apr 16, 2015·Circulation. Heart Failure·Kirsten S DoransMurray A Mittleman
Jan 31, 2013·The American Journal of Forensic Medicine and Pathology·Quan-Yong HuangShui-Ping Liu

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