Abstract
Although alcohol drinking increases blood pressure and heavy drinking has been associated with alcoholic cardiomyopathy, little is known about the association between light to moderate drinking and risk of heart failure (HF) in hypertensive subjects. Thus, the association between light to moderate drinking and incident HF in 5,153 hypertensive male physicians who were free of stroke, myocardial infarction, or major cancers at baseline was prospectively examined. Alcohol consumption was self-reported and classified as <1, 1 to 4, 5 to 7, and >or=8 drinks/week. HF was ascertained using follow-up questionnaires and validated using Framingham criteria. Average age was 58 years, and about 70% of subjects consumed 1 to 7 drinks/week. A total of 478 incident HF cases occurred in this cohort during follow-up. Compared with subjects consuming <1 drink/week, hazard ratios for HF were 0.89 (95% confidence interval [CI] 0.70 to 1.12), 0.72 (95% CI 0.57 to 0.91), and 0.38 (95% CI 0.20 to 0.72) for alcohol consumption of 1 to 4, 5 to 7, and >or=8 drinks/week after adjustment for age, body mass index, smoking, randomization group, use of multivitamins, vegetable consumption, breakfast cereal, exercise, and history of atrial fibrillation, resp...Continue Reading
References
Jan 1, 1991·Life Sciences·D ColantonioP Pasqualetti
Feb 1, 1991·The American Journal of Cardiology·M KupariA Suokas
Aug 1, 1991·Drug and Alcohol Dependence·B D BertoletC J Pepine
Jul 20, 1989·The New England Journal of Medicine·UNKNOWN Steering Committee of the Physicians' Health Study Research Group
Dec 16, 1993·The New England Journal of Medicine·J M GazianoC H Hennekens
Feb 1, 1997·Alcoholism, Clinical and Experimental Research·C GianoulakisJ Gutkowska
May 20, 1998·American Heart Journal·C J McKennaD D Sugrue
Oct 28, 1999·American Heart Journal·K J MukamalM A Mittleman
Jun 8, 2001·Journal of Hypertension·N NakanishiK Tatara
Sep 28, 2001·Diabetes·K M ConigraveE B Rimm
Feb 6, 2002·Annals of Internal Medicine·Craig R WalshDaniel Levy
Jun 3, 2004·Journal of the American College of Cardiology·David AguilarScott D Solomon
Nov 24, 2004·Nature Medicine·Rei ShibataKenneth Walsh
Dec 2, 2004·European Heart Journal·A ImhofW Koenig
Feb 8, 2006·Diabetologia·L L J KoppesR J Heine
Aug 23, 2006·The American Journal of Cardiology·Luc DjousséRobert Curtis Ellison
Dec 13, 2006·Archives of Internal Medicine·Augusto Di CastelnuovoGiovanni de Gaetano
May 12, 2007·Diabetologia·J W J BeulensH F J Hendriks
Jul 20, 2007·Obesity·Luc DjousséDavid S Siscovick
Citations
Jul 16, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Paloma Gil-BernabeYoshiyuki Takei
Sep 8, 2012·ISRN Cardiology·Javed Butler
Aug 6, 2014·Mayo Clinic Proceedings·Chao HuangQi-Qiang He
Jul 30, 2011·Clinical and Experimental Hypertension : CHE·Mingliang GuWenquan Niu
Feb 18, 2012·International Journal of Cardiology·Rajesh Movva, Vincent M Figueredo
Jan 30, 2010·Progress in Cardiovascular Diseases·Eric H Awtry, George J Philippides
Nov 17, 2015·International Journal of Cardiology·Katalin GémesKenneth J Mukamal
Apr 2, 2009·European Journal of Heart Failure·Irma LaonigroEmanuele Altomare
Mar 23, 2012·Nursing & Health Sciences·Oksoo KimHae Ok Jeon
Apr 12, 2011·The American Journal on Addictions·Yann Le Strat, Philip Gorwood
Sep 17, 2013·Alcoholism, Clinical and Experimental Research·Elia C El HajjJason D Gardner
Feb 14, 2014·Journal of Neurochemistry·Inna I Kruman, Anna-Kate Fowler
Mar 4, 2014·Mayo Clinic Proceedings·James H O'KeefeCarl J Lavie
Jun 24, 2015·Nature Reviews. Cardiology·Joaquim Fernández-Solà
Jul 20, 2016·PloS One·Suhas SureshchandraIlhem Messaoudi
Mar 1, 2018·Frontiers in Pharmacology·Adam ObadSima T Tarzami
May 5, 2010·Circulation·Simona CostanzoGiovanni de Gaetano
Apr 16, 2015·Circulation. Heart Failure·Kirsten S DoransMurray A Mittleman
Jan 31, 2013·The American Journal of Forensic Medicine and Pathology·Quan-Yong HuangShui-Ping Liu