Alcohol consumption and incident diabetes: The Atherosclerosis Risk in Communities (ARIC) study

Diabetologia
Xintong HeElizabeth Selvin

Abstract

The aim of this study was to evaluate the prospective association between baseline and 9 year change in alcohol consumption and long-term risk of diabetes and whether these associations might be modified by sex and/or BMI. We conducted a prospective analysis of 12,042 Atherosclerosis Risk in Communities (ARIC) study participants without prevalent diabetes (55% women, 78% white, mean age 54 years). Alcohol consumption was assessed at visit 1 (1987-1989) and visit 4 (1996-1998). We used Cox models to estimate hazard ratios for diabetes risk by baseline drinking categories and change in alcohol consumption, stratified by sex and obesity status. During a median follow-up of 21 years, there were 3795 incident cases of diabetes. Among women, consuming 8-14 drinks/week was associated with a significantly lower risk of diabetes (HR 0.75, 95% CI 0.58, 0.96) compared with current drinkers consuming ≤1 drink/week. Among men, consuming 8-14 drinks/week was associated with a borderline significant lower risk of diabetes (HR 0.84, 95% CI 0.70, 1.00) and consuming >14 drinks/week was associated with a significantly lower risk of diabetes (HR 0.81, 95% CI 0.67, 0.97) (pinteraction < 0.01 for sex). For both sexes, among current drinkers, there ...Continue Reading

References

Nov 1, 1982·The American Journal of Clinical Nutrition·J A BaeckeJ E Frijters
Feb 15, 2001·Current Opinion in Lipidology·A van Tol, H F Hendriks
Jan 18, 2003·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·D T FuruyaU F Machado
Jun 9, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·A M HodgeG G Giles
Oct 31, 2009·Diabetes Care·Dolly O BaliunasJürgen Rehm
Feb 13, 2010·Journal of Atherosclerosis and Thrombosis·Atsushi HozawaHirotsugu Ueshima
Sep 30, 2010·Diabetes·Michel M JoostenEric B Rimm
Feb 22, 2011·International Journal of Epidemiology·Emilie AgardhAnna Sidorchuk
Apr 16, 2014·Annals of Internal Medicine·Elizabeth SelvinJosef Coresh
Sep 6, 2014·Diabetes & Metabolism·E KoloverouUNKNOWN ATTICA Study group
Oct 25, 2014·Journal of Studies on Alcohol and Drugs·Ichiro Wakabayashi
Jan 7, 2017·Journal of the American College of Cardiology·Michael H Criqui, Isac C Thomas
Apr 21, 2018·Lancet·Jason Connor, Wayne Hall

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Citations

May 28, 2019·Biological Trace Element Research·Xiao ChenZhongqiu Wang
Jul 17, 2020·The Tohoku Journal of Experimental Medicine·Yu HatanoKimihiko Akimoto
Aug 11, 2020·Current Atherosclerosis Reports·Hongyun WangJunjie Xiao
Apr 8, 2021·Journal of Public Health·Xingxia ZhangKa Li

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