PMID: 28499102May 13, 2017Paper

Alcohol Consumption and Mortality From Coronary Heart Disease: An Updated Meta-Analysis of Cohort Studies

Journal of Studies on Alcohol and Drugs
Jinhui ZhaoTanya Chikritzhs

Abstract

Previous meta-analyses estimate that low-volume alcohol consumption protects against coronary heart disease (CHD). Potential errors in studies include systematic misclassification of drinkers as abstainers, inadequate measurement, and selection bias across the life course. Prospective studies of alcohol consumption and CHD mortality were identified in scholarly databases and reference lists. Studies were coded for potential abstainer biases and other study characteristics. The alcohol-CHD risk relationship was estimated in mixed models with controls for potential biases. Stratified analyses were performed based on variables identified as potential effect modifiers. Fully adjusted meta-analysis of all 45 studies found significantly reduced CHD mortality for current low-volume drinkers (relative risk [RR] = 0.80, 95% CI [0.69, 0.93]) and all current drinkers (RR = 0.88, 95% CI [0.78, 0.99]). There was evidence of effect modification by cohort age, gender, ethnicity, and heart health at baseline. In stratified analyses, low-volume consumption was not significantly protective for cohorts ages 55 years or younger at baseline (RR = 0.95, 95% CI [0.75, 1.21]), for studies controlling for heart health (RR = 0.87, 95% CI [0.71, 1.06]), ...Continue Reading

Citations

Oct 7, 2018·Nature Reviews. Neurology·Miia KivipeltoTiia Ngandu
Jan 15, 2019·The Cochrane Database of Systematic Reviews·Samantha CukierJames D Sargent
Nov 7, 2019·Current Pharmaceutical Design·Andreea CorinaManfredi Rizzo
Jan 6, 2018·Neurotoxicity Research·Yousef TizabiRobert E Taylor
Jul 6, 2019·Alcoholism, Clinical and Experimental Research·Katherine M KeyesLinda P Fried
Aug 1, 2019·Journal of the American Geriatrics Society·Benjamin H HanJoseph J Palamar
Dec 4, 2019·Canadian Journal of Public Health = Revue Canadienne De Santé Publique·Justin T SorgeBrian Ferguson
Jun 12, 2020·Alcoholism, Clinical and Experimental Research·Natalie R DayaMariana Lazo
Dec 27, 2017·Journal of Cellular and Molecular Medicine·Yan-Yan LiGe Gong
Mar 21, 2018·International Journal of Environmental Research and Public Health·Chandra L JacksonEric B Rimm
Apr 3, 2018·Annual Review of Public Health·Marissa B Esser, David H Jernigan
May 11, 2018·Current Opinion in Psychiatry·Allaman Allamani
Dec 20, 2018·Drug and Alcohol Review·Tim Stockwell
Jan 15, 2020·European Cardiology·Amelia Carro, Josefa María Panisello
Dec 11, 2019·International Journal of Environmental Research and Public Health·Adam SherkTanya Chikritzhs
Feb 23, 2020·American Journal of Public Health·Gemma MitchellJim McCambridge
Mar 22, 2019·Current Nutrition Reports·Jürgen RehmKevin D Shield
Feb 27, 2020·Nutrients·Joaquim Fernández-Solà
Oct 1, 2019·Alcoholism, Clinical and Experimental Research·Marcia RussellMaurizio Trevisan
Aug 11, 2019·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Youngyo KimEdward L Giovannucci
Dec 29, 2020·Addictive Behaviors Reports·Nina LockwoodJohn Larsen
Dec 23, 2020·Alcoholism, Clinical and Experimental Research·Won Kim CookLibo Li
Aug 18, 2018·Journal of the American College of Cardiology·Edward YuFrank B Hu
Jan 21, 2021·European Journal of Pain : EJP·Emma Kwan-Yee HoPaulo Ferreira
Apr 13, 2021·Alcoholism, Clinical and Experimental Research·Dan V BlalockMatthew L Maciejewski

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.