PMID: 8986195Dec 1, 1996Paper

Alcohol consumption, gamma-glutamyl transpeptidase (GGT), and pulmonary function: a cross-sectional and longitudinal study in working men

Alcoholism, Clinical and Experimental Research
M ZureikF Neukirch

Abstract

Epidemiological studies of the relationships between pulmonary function and reported alcohol intake showed inconsistent results. The use of biological markers of alcohol is needed. The objective of this study was to assess the relationships of alcohol consumption, assessed by a standardized questionnaire, and gamma-glutamyl transpeptidase (GGT), to forced expiratory volume in 1 sec (FEV1) level and decline over 10 years, in working men. Three hundred twenty-eight policemen aged 22-55 years were examined in 1980 (first survey) and again in 1990 (second survey). The two cross-sectional analyses used the 1980 data and the 1990 data separately. Longitudinal analysis used 1980 alcohol consumption and GGT values, and 10-year FEV1 decline. In both cross-sectional surveys, elevated alcohol consumption was significantly associated with impaired age-adjusted and height-adjusted FEV1. Further adjustment for smoking habit, education level, and asthmatic status did not alter these results. An increase of 25 g/day of alcohol was associated with 50.0 ml (95% confidence interval: 1.5 to 98.5) and 55.3 ml (95% confidence interval: 7.8 to 102.8) decrease of corresponding multivariate-adjusted FEV1 in 1980 and in 1990, respectively. GGT was also ...Continue Reading

References

Jul 1, 1977·The American Journal of Medicine·H O Heinemann
Dec 1, 1990·Chest·F NeukirchR Pariente
Nov 3, 1990·BMJ : British Medical Journal·G Rose, S Day
Aug 1, 1989·The American Review of Respiratory Disease·E GarshickM J Miller
Jul 1, 1989·Journal of Internal Medicine·P LangeP Schnohr
May 1, 1988·The American Review of Respiratory Disease·P LangeP Schnohr
Mar 1, 1988·The American Review of Respiratory Disease·J D Brain
May 1, 1983·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·F D McCoolM G Marin
Sep 1, 1994·American Journal of Epidemiology·B L RodriguezE B Marcus
Mar 27, 1993·Lancet·F KauffmannR Oriol

❮ Previous
Next ❯

Citations

Jan 14, 2003·Sleep & Breathing = Schlaf & Atmung·Holger J SchünemannMaurizio Trevisan
Dec 11, 2003·British Journal of Sports Medicine·Y J ChengS N Blair
Jan 15, 2005·Clinical and Experimental Pharmacology & Physiology·Kenichiro TanedaKotaro Ozasa

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.