PMID: 7034784Feb 2, 1982Paper

Alcohol dehydrogenase activity in rat kidney cortex stimulated by oestradiol

Biochimica Et Biophysica Acta
Z Dembić, I Sabolić

Abstract

Sex differences in alcohol dehydrogenase activity, determined by the influence of oestrogen hormones, were found to exist in the rat kidney. Oestradiol, but neither testosterone nor progesterone, was shown to be a powerful stimulator of kidney alcohol dehydrogenase activity in rats, maximally 6- to 8-times over control values. The Michaelis-Menten constant for acetaldehyde of both non-stimulated and oestradiol-stimulated kidney alcohol dehydrogenases was found to be similar, 6.7 x 10(-5) M and 7.8 x 10(-5) M, respectively. Actinomycin D was shown to have an additive effect (superinduction) on the oestradiol-induced increase in kidney enzyme activity. The findings suggest the possibility of the higher contribution of kidneys in ethanol intake and ethanol hepatic disease.

References

Jul 1, 1978·Alcoholism, Clinical and Experimental Research·G G GordonC S Lieber
Jul 27, 1979·Biochemical and Biophysical Research Communications·C Wu
Aug 13, 1979·Biochemical and Biophysical Research Communications·F MorenoG Strohmeyer
Jun 14, 1978·Biochemical and Biophysical Research Communications·C Wu
Jan 1, 1979·Metabolism: Clinical and Experimental·G G GordonC S Lieber
Apr 15, 1976·Biochemical Pharmacology·E Mezey
Dec 1, 1972·The Journal of Clinical Endocrinology and Metabolism·L P Bullock, W C Bardin
Jul 1, 1969·Biochemical Pharmacology·L Goldberg, U Rydberg
Feb 1, 1972·Journal of Neurochemistry·N H Raskin, L Sokoloff
Aug 1, 1972·Kidney International·J R DeVriesD D Fanestil
Jul 7, 1971·Nature: New Biology·R DofukuS Ohno
Nov 1, 1965·Biochimica Et Biophysica Acta·J R Dunstone, W T Morgan
Sep 1, 1970·Experimental Cell Research·T H SchieblerC Pilgrim
May 1, 1969·European Journal of Biochemistry·A K Rawat
Oct 1, 1960·Klinische Wochenschrift·E SCHMIDT, F W SCHMIDT
Oct 17, 1959·Nature·J A LARSEN

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Citations

Jul 20, 2007·Pflügers Archiv : European journal of physiology·Ivan SabolićGerhard Burckhardt
Mar 2, 1994·Biochemical Pharmacology·A A Nikiforov, I B Ostretsova
Feb 19, 2011·Chemico-biological Interactions·Aída Hernández-TobíasHéctor Riveros-Rosas
Jun 27, 2015·Toxicology and Applied Pharmacology·Mahmoud M El-Mas, Abdel A Abdel-Rahman
Oct 1, 1993·Metabolism: Clinical and Experimental·D W Crabb, R Sidhu
Sep 1, 1987·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R E CuellarD H Van Thiel
Oct 1, 1987·Journal of Applied Toxicology : JAT·J T JamesM R Landauer
Aug 1, 1991·Archives of Biochemistry and Biophysics·M QulaliD W Crabb

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