Alcohol dependence, other psychiatric disorders, and health-related quality of life: a replication study in a large random sample of enrollees in the Veterans Health Administration

The American Journal of Drug and Alcohol Abuse
David KalmanLewis E Kazis

Abstract

The purpose of this study was to investigate the relationship between alcohol dependence and health-related quality of life (HRQoL) in people with and without other selected psychiatric disorders. A sample of 127,308 Veterans Health Administration enrollees completed a survey that included questions about alcohol use and the Veterans SF-36, a well-validated measure of HRQoL. In addition, a Veterans Administration database was used to obtain respondents' past-year history of alcohol dependence and other psychiatric disorders. Comorbid psychiatric disorders significantly moderated or attenuated the relationship between alcohol dependence and HRQoL. Respondents with a history of alcohol dependence plus one or more other psychiatric disorders had significantly lower HRQoL in domains pertaining to psychological and social functioning than respondents with alcohol dependence only. Effect size differences (mean differences of clinical groups/pooled standard deviation) were large (greater than 0.80 of one standard deviation). Respondents with a history of alcohol dependence only vs. no history of alcohol dependence had poorer HRQoL. Effect size differences were small to moderate (between 0.20 and 0.50 of one standard deviation). Findin...Continue Reading

References

Feb 1, 1992·Alcoholism, Clinical and Experimental Research·B J PowellE F Brown
May 1, 1995·Journal of Substance Abuse Treatment·H FrancoJ Patterson
Feb 5, 1996·The Medical Journal of Australia·C D HolmanM G Winter
Mar 24, 1998·Archives of General Psychiatry·S F GreenfieldJ Michael
May 23, 1998·Journal of Studies on Alcohol·R P MurrayC M Beaudoin
Nov 5, 1998·Addictive Behaviors·E B Raimo, M A Schuckit
Dec 16, 1998·The American Journal of Drug and Alcohol Abuse·J B DaeppenB Yersin
Aug 14, 1999·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·L E KazisD R Miller
Sep 23, 2000·The American Journal on Addictions·H M PettinatiC P O'Brien
Sep 7, 2001·Drug and Alcohol Dependence·D B KandelM Davies

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Citations

Apr 28, 2006·Current Opinion in Psychiatry·Michael F Baigent
Apr 5, 2012·Alcoholism, Clinical and Experimental Research·Nataliya ZhabenkoKirk J Brower
Jul 2, 2016·Alcoholism, Clinical and Experimental Research·Elizabeth RalevskiIsmene Petrakis
Nov 26, 2008·AIDS Patient Care and STDs·P Todd KorthuisUNKNOWN HIV Research Network
Mar 26, 2015·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Luciana D SilvaEliane D Gontijo
Dec 24, 2015·The American Journal on Addictions·Chiao-Wen LanBrandon D L Marshall
Sep 7, 2012·Health and Quality of Life Outcomes·Irina BenaigesAna Adan
Dec 20, 2015·Alcoholism, Clinical and Experimental Research·Ismene L PetrakisElizabeth Ralevski
Jul 3, 2015·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Michelle E MartinezGeorge Sayre

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