PMID: 8986198Dec 1, 1996Paper

Alcohol effects on the heritability of EEG spectral power

Alcoholism, Clinical and Experimental Research
J SorbelJ C Christian

Abstract

To estimate the effects of a moderate dose of alcohol on heritability of the EEG power spectrum, 53 monozygotic and 38 like-sexed dizygotic Caucasian twin pairs (aged 30.0 +/- 7.0 years) were studied. Subjects were asked not to drink alcohol for 2 days and to fast after midnight before a protocol of: (1) a low fat meal at 8:00 AM; (2) a baseline EEG recording; (3) ingestion of alcohol over 10 min, which raised the breath alcohol concentration to 0.057 +/- 0.017% (SD); followed by (4) a postalcohol EEG recording 35.1 +/- 5.7 (SD) min after the start of drinking. One previous study (Propping, P., Hum. Genet. 35: 309-334, 1977) found that heritability (H2), the fraction of total variance in the EEG power that is attributable to genetic influences, increased after alcohol administration. In the current study, H2 of log-transformed, body-weight-adjusted spectral band power increased after alcohol for the theta-, alpha-slow, alpha-fast, beta-slow, and beta-fast bands (from an average of 0.47 to an average of 0.80). The increase in heritability was accompanied by a significant decrease in the within-pair differences of monozygotic cotwins for all of the same frequency bands except beta-fast. Because within-pair differences are expecte...Continue Reading

References

Feb 1, 1976·Electroencephalography and Clinical Neurophysiology·O D CreutzfeldtW Wuttke
Feb 1, 1979·Electroencephalography and Clinical Neurophysiology·R Coppola
Apr 1, 1990·Electroencephalography and Clinical Neurophysiology·V E PollockS A Lyness
Mar 1, 1994·Electroencephalography and Clinical Neurophysiology·S O'ConnorT K Li
Jun 1, 1993·Electroencephalography and Clinical Neurophysiology·H L CohenH Begleiter

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Citations

Dec 21, 2006·Behavior Genetics·Yongqiang TangHenri Begleiter
Oct 19, 2002·Biological Psychology·C E M van Beijsterveldt, G C M van Baal
Aug 3, 1999·Neuroscience·C L EhlersC B Nemeroff
Mar 9, 1999·Alcoholism, Clinical and Experimental Research·P R Finn, A Justus
Apr 9, 1999·Alcoholism, Clinical and Experimental Research·S O'ConnorJ C Christian
Sep 2, 1999·Alcoholism, Clinical and Experimental Research·V A RamchandaniT K Li
Apr 18, 2014·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Andrey P Anokhin
Mar 27, 2007·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Yongqiang TangHenri Begleiter
Apr 19, 2005·Alcoholism, Clinical and Experimental Research·George Fein, Jennifer Allen
Dec 31, 2003·Psychophysiology·Elena V OrekhovaSergey B Malykh
Oct 3, 2008·Alcoholism, Clinical and Experimental Research·Robert E TaylorDenise M Scott
Jan 5, 2010·Psychiatry Investigation·Soo Young BhangJoon Ho Ahn

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