Alcoholism and neuro-immune-endocrine interactions: physiochemical aspects

Biochemical and Biophysical Research Communications
John J Haddad

Abstract

The role of alcohol consumption and alcoholism as an addiction in regulating the chemistry of the brain and its physiology has gained a backlog of interest over the past few decades. Besides the notion that alcohol acts as a brain depressant, the molecular mechanisms and neuronal interactions are not well understood. Emerging evidence implicates alcohol as a neurochemical messenger that influences a cross talk amongst the nervous, immune, and endocrine systems. Specifically, alcohol acts as a crucial regulator of the hypothalamic-pituitary-adrenal (HPA) axis, thereby modulating the release of hormones, particularly adrenocorticotropic hormone (ACTH) and corticosterone (CORT). It is the aim of this review, therefore, to investigate current concepts on how alcohol, particularly ethanol, and alcoholism affect neuro-immune-endocrine neurochemical interactions via the regulation of the HPA axis, taking into consideration bio-behavioral and physiochemical aspects.

References

Jan 1, 1992·Psychoneuroendocrinology·L Buydens-Branchey, M H Branchey
Jun 1, 1991·Alcoholism, Clinical and Experimental Research·A J RobertsL D Keith
Sep 1, 1990·Psychiatry Research·A RoyM Linnoila
Jun 1, 1991·The Journal of Clinical Endocrinology and Metabolism·G S Wand, A S Dobs
Nov 1, 1990·Neuroendocrinology·R L Spencer, B S McEwen
Jun 1, 1990·Alcoholism, Clinical and Experimental Research·S R GeorgeC A Naranjo
Dec 1, 1989·Alcoholism, Clinical and Experimental Research·U HalbreichM Galanter
Aug 1, 1987·Alcoholism, Clinical and Experimental Research·G M KnudsenH Hasselbalch
May 1, 1988·Medical Toxicology and Adverse Drug Experience·B AdinoffM Linnoila
Dec 1, 1982·Journal of Affective Disorders·S D TargumM T Advani
Jan 1, 1983·Alcoholism, Clinical and Experimental Research·J R de La FuenteA F Schatzberg
Feb 1, 1984·Acta Psychiatrica Scandinavica·M T Abou-SalehA Coppen
Oct 1, 1993·Alcoholism, Clinical and Experimental Research·S Lee, C Rivier
Oct 1, 1993·Alcoholism, Clinical and Experimental Research·C Rivier
May 1, 1993·Journal of Gastroenterology and Hepatology·J A McDonaldG W McCaughan
Dec 29, 1995·Annals of the New York Academy of Sciences·R L EskayC Hamelink
Feb 1, 1996·Alcoholism, Clinical and Experimental Research·J WeinbergC Gianoulakis
Apr 1, 1996·Alcoholism, Clinical and Experimental Research·C Rivier
Mar 1, 1996·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·F LamblinP de Witte
Jul 1, 1997·Pharmacology, Biochemistry, and Behavior·T J PhillipsC N Lessov
Jan 23, 1998·Alcoholism, Clinical and Experimental Research·C Rivier
Jun 3, 1999·Frontiers in Bioscience : a Journal and Virtual Library·C Rivier
Aug 12, 1999·Alcoholism, Clinical and Experimental Research·G S WandP Giggey
May 2, 2000·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·D L MangoldG S Wand
Jan 5, 2001·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·H KinoshitaM S Harbuz
Jan 5, 2001·Alcoholism, Clinical and Experimental Research·D D RasmussenC W Wilkinson
May 2, 2001·Biological Psychiatry·F KieferK Wiedemann
May 24, 2001·Alcoholism, Clinical and Experimental Research·W HundtF Holsboer
May 24, 2001·Alcoholism, Clinical and Experimental Research·J C UmhauA D George
Aug 29, 2001·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·H F MoselhyA Kahn

❮ Previous
Next ❯

Citations

Jul 4, 2008·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·John KaravitisElizabeth J Kovacs
Sep 11, 2010·Disease Models & Mechanisms·Trupti KawliMan-Wah Tan
Feb 26, 2008·Environment International·Kazuaki TakahashiKanehisa Morimoto
Sep 14, 2007·Alcoholism, Clinical and Experimental Research·Eve R SchneiderBartley G Hoebel
Dec 7, 2011·Alcoholism, Clinical and Experimental Research·Christa M HelmsKathleen A Grant
Nov 26, 2013·The American Journal of Drug and Alcohol Abuse·Irene Joy I Dela PeñaJae Hoon Cheong
May 18, 2016·Addiction Biology·Željko ČupićVladana Vukojević
Mar 8, 2012·Psychiatry Investigation·Jee Wook KimIhn-Geun Choi
Jan 1, 2008·Clinical Medicine. Circulatory, Respiratory and Pulmonary Medicine·Peyman OtmishiJerry Yu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antitubercular Agents (ASM)

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Antitubercular Agents

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Related Papers

The Journal of Clinical Endocrinology and Metabolism
Gary S Wand, A S Dobs
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Y AdachiR G Thurman
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
T UesugiR G Thurman
© 2021 Meta ULC. All rights reserved