PMID: 3760899Sep 1, 1986Paper

Aleukaemic leukostasis in a case of large cell non-Hodgkin's lymphoma: report of a case with a distinctive central nervous system involvement

Journal of Neurology, Neurosurgery, and Psychiatry
S JainR E Sage

Abstract

A 52-year-old man with large cell non-Hodgkin's lymphoma developed a unique pattern of central nervous system involvement by lymphoma while in apparent systemic remission. Despite intermittent neurological episodes suggestive of CNS involvement by lymphoma no evidence of CNS lymphoma was found on repeated cerebrospinal fluid and brain CT scan examinations. At necropsy widespread occlusion of cerebral blood vessels by malignant lymphoid cells was observed with extensive tissue necrosis and haemorrhages. Leukaemic involvement of peripheral blood was not detected on repeated blood film examinations during life.

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Citations

Sep 1, 1987·Baillière's Clinical Haematology·M A LichtmanJ M Rowe
Oct 1, 1991·Middle East Journal of Anesthesiology·A Taha
Apr 18, 2007·Orvosi hetilap·Mónika SzotsZsolt Illés
Jan 1, 1994·British Journal of Neurosurgery·P J KaneA Jenkins
Mar 29, 2016·Hematological Oncology·Alaa M AliAmanda F Cashen
Jun 1, 1995·Acta Neurologica Scandinavica·J E ChapinR N Mandler

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