Alexidine versus chlorhexidine for endodontic irrigation with sodium hypochlorite

European Journal of Dentistry
Kanav JainTwisha Adlakha

Abstract

The objective of this study was to chemically evaluate precipitate formation on irrigation by different concentrations of chlorhexidine (CHX) and alexidine (ALX) with sodium hypochlorite (NaOCl). Six test tubes were prepared with 1 ml of 4% NaOCl. One milliliter of 2%, 1%, 0.5%, and 0.25% ALX was added to the first four, and in the last two, 1 ml of 2% CHX and 0.2% CHX was added, respectively. Samples were observed for color changes or precipitates at multiple time intervals. All solutions were then centrifuged at 1000 rpm for 10 min and re-examined for precipitates. This process was repeated twice. Fifty freshly extracted premolars were biomechanically prepared, dried, divided into two groups, and irrigated with 10 ml of 4% NaOCl and 10 ml of 2% ALX (Group 1) and 10 ml of 4% NaOCl and 10 ml of 2% CHX (Group 2). These samples were sectioned and observed for precipitates on the dentinal surfaces by scanning electron microscopy (SEM). The color of the solution of ALX and NaOCl stayed transparent and no precipitate was observed. A color change was noted immediately on mixing CHX and NaOCl which did not change with time. Precipitates were only observed in the solutions of CHX with NaOCl and after centrifuging them. SEM views also s...Continue Reading

Citations

Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Barbara CzopikMichał Woźniakiewicz
Apr 16, 2021·European Journal of Medicinal Chemistry·Deepika KathuriaPrasad V Bharatam
Dec 23, 2021·European Journal of Dentistry·Alexandra Aparecida TanomaruMarcos Frozoni

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Methods Mentioned

BETA
scanning electron microscopy
fluorescence displacement assay
a
X-ray
PCA

Software Mentioned

Statistical Package for the Social Sciences Software ( SPSS

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