PMID: 2495743Mar 1, 1989Paper

Alfentanil requirement in Crohn's disease. Increased alfentanil dose requirement in patients with Crohn's disease

Anaesthesia
B J Gesink-van der VeerJ G Bovill

Abstract

The dose requirement of alfentanil as a supplement to nitrous oxide anaesthesia was studied in 13 patients with Crohn's disease and seven control patients all of whom underwent laparotomy. Alfentanil was administered as a variable rate infusion with supplemental bolus injections titrated to the patient's needs. The alfentanil requirement was independent of the duration of surgery and was significantly higher in patients with Crohn's disease than in control patients. The results indicate that Crohn's disease alters the dose requirement of alfentanil.

Citations

Jun 3, 1999·The Surgical Clinics of North America·I Power, S Barratt
Jan 25, 2006·Paediatric Anaesthesia·Mark W CrawfordBasem Naser
Jun 3, 1999·The Surgical Clinics of North America·M L Austrup, G Korean

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