ALGEBRA: ALgorithm for the heterogeneous dosimetry based on GEANT4 for BRAchytherapy

Physics in Medicine and Biology
Hossein AfsharpourLuc Beaulieu

Abstract

Task group 43 (TG43)-based dosimetry algorithms are efficient for brachytherapy dose calculation in water. However, human tissues have chemical compositions and densities different than water. Moreover, the mutual shielding effect of seeds on each other (interseed attenuation) is neglected in the TG43-based dosimetry platforms. The scientific community has expressed the need for an accurate dosimetry platform in brachytherapy. The purpose of this paper is to present ALGEBRA, a Monte Carlo platform for dosimetry in brachytherapy which is sufficiently fast and accurate for clinical and research purposes. ALGEBRA is based on the GEANT4 Monte Carlo code and is capable of handling the DICOM RT standard to recreate a virtual model of the treated site. Here, the performance of ALGEBRA is presented for the special case of LDR brachytherapy in permanent prostate and breast seed implants. However, the algorithm is also capable of handling other treatments such as HDR brachytherapy.

References

Jan 7, 2003·Medical Physics·B R B WaltersD W O Rogers
Feb 16, 2006·Medical Physics·Omar Chibani, Jeffrey F Williamson
Aug 2, 2006·Medical Physics·Jean-François CarrierRené Roy
Jul 21, 2009·Medical Physics·Mark J RivardLuc Beaulieu

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Citations

Oct 6, 2014·Medical Physics·Charles-Antoine Collins FeketeLuc Beaulieu
Jul 17, 2014·The British Journal of Radiology·P PapagiannisP Karaiskos
Feb 24, 2015·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Charles-Antoine Collins FeketeLuc Beaulieu
Jun 19, 2016·Brachytherapy·Charles-Antoine Collins-FeketeLuc Beaulieu
Sep 9, 2016·Journal of Radiation Research·Hiroyuki OkamotoJun Itami
Oct 4, 2016·Brachytherapy·Áine MaxwellPeter J Hoskin
Feb 14, 2015·Journal of Applied Clinical Medical Physics·Evaggelos PantelisPanagiotis Papagiannis
Sep 17, 2014·Technology in Cancer Research & Treatment·Jiankui YuanBarry Wessels
May 13, 2017·Brachytherapy·François Therriault-ProulxSam Beddar
Aug 11, 2018·Physics in Medicine and Biology·Gabriel FamulariShirin A Enger
Mar 4, 2014·Physics in Medicine and Biology·Robin HillClive Baldock
Jun 26, 2015·Physics in Medicine and Biology·Åsa Carlsson TedgrenLuc Beaulieu
Mar 15, 2014·Physics in Medicine and Biology·G P FonsecaF Verhaegen
Jun 11, 2015·Physics in Medicine and Biology·Éric BonenfantPhilippe Després
Nov 3, 2016·Physics in Medicine and Biology·Marc J P ChamberlandRowan M Thomson
Jun 11, 2015·Physics in Medicine and Biology·Yannick LemaréchalDimitris Visvikis
May 19, 2016·Physics in Medicine and Biology·Evaggelos PantelisPanagiotis Papagiannis
Sep 12, 2014·Physics in Medicine and Biology·Gabriel Paiva FonsecaFrank Verhaegen
Apr 27, 2021·Brachytherapy·Francisco BerumenLuc Beaulieu

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