PMID: 2494389Jan 1, 1989

Algorithm for computing oxygen dissociation curve with pH, PCO2, and CO in sheep blood

Journal of Biomedical Engineering
M Sharan, A S Popel

Abstract

By extending the study of Samaja and Gattinoni, an algorithm is described for computing the oxygen dissociation curve with variations in pH, PCO2, and CO in homozygous HbB sheep blood. The difference in the values of O2 pressure at 50% saturation in presence of CO computed from the present algorithm and Hill's equation does not exceed 0.5%. It is shown that O2 affinity increases as the concentration of CO or pH increases or PCO2 decreases. The algorithm is convenient for representing the oxygen dissociation curve with variation in pH, PCO2 and the concentration of CO in modelling oxygen transport in sheep blood even under hypoxic conditions.

References

Sep 1, 1978·Respiration Physiology·M Samaja, L Gattinoni

Citations

Jan 1, 1991·Comparative Biochemistry and Physiology. A, Comparative Physiology·A Flisińska-BojanowskaM Komosa
Oct 5, 2010·Acta Physiologica·Ranjan K Pradhan, V S Chakravarthy
Feb 17, 2001·American Journal of Respiratory and Critical Care Medicine·T C KreckM P Hlastala
Oct 20, 2014·Forensic Science, Medicine, and Pathology·Wolf SchweitzerSebastian Winklhofer
Nov 3, 2012·Microvascular Research·Bumseok NamgungSangho Kim
Oct 20, 2009·Nanomedicine : Nanotechnology, Biology, and Medicine·Tad Hogg, Robert A Freitas
May 24, 2011·Atherosclerosis·Phapanin CharoenpholOmolola Eniola-Adefeso
Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M K AtalayJ R Forder
Aug 5, 2003·Journal of Applied Physiology·K O'NeillM F Vidal Melo
Dec 18, 2001·Journal of Applied Physiology·Luiz A VaneGeorge C Kramer
Dec 18, 2001·Journal of Applied Physiology·R Scott HarrisJosé G Venegas

Related Concepts

Carbon Dioxide
Carbon Monoxide
Hydrogen-Ion Concentration
Statistical Programs, Computer Based
Dioxygen
Dall Sheep

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