Algorithm for multi-curve-fitting with shared parameters and a possible application in evoked compound action potential measurements

Biomedical Engineering Online
Philipp SpitzerErwin Hochmair

Abstract

Experimental results are commonly fitted by determining parameter values of suitable mathematical expressions. In case a relation exists between different data sets, the accuracy of the parameters obtained can be increased by incorporating this relationship in the fitting process instead of fitting the recordings separately. An algorithm to fit multiple measured curves simultaneously was developed. The method accounts for parameters that are shared by some curves. It can be applied to either linear or nonlinear equations. Simulated noisy "measurement results" were created to compare the introduced method to the "straight forward" way of fitting the curves separately. The analysis of the simulated measurements confirm, that the introduced method yields more accurate parameters compared to the ones gained by fitting the measurements separately. Therefore it needs more computer time. As an example, the new fitting algorithm is applied to the measurements of the evoked compound action potentials (ECAP) of the auditory nerve: This leads to promising ideas to reduce artefacts generated by the measuring process. The introduced fitting algorithm uses the relationship between multiple measurement results to increase the accuracy of the ...Continue Reading

References

Sep 1, 1990·The Journal of the Acoustical Society of America·C J BrownB Gantz
Jan 1, 1997·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·J HelmsI Hochmair-Desoyer
Jan 1, 1997·Annals of Biomedical Engineering·L A Geddes

❮ Previous
Next ❯

Citations

Sep 1, 2012·Journal of Integrative Neuroscience·T SaleewongS Bongsebandhu-phubhakdi
Oct 20, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ben R DickieChris J Rose
Jan 24, 2015·Physical Review Letters·Y RomachF Jelezko

❮ Previous
Next ❯

Methods Mentioned

BETA
cochlear implant
cochlear implants

Software Mentioned

ArtResearch

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.